Chapter·BiostatisticsP-values and confidence intervals

Relationship between CIs and hypothesis testingDownloads

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1

Group of 100 medical students took an end of the year exam. The mean score on the exam was 70%, with a standard deviation of 25%. The professor states that a student's score must be within the 95% confidence interval of the mean to pass the exam. Which of the following is the minimum score a student can have to pass the exam?

A45%

B63.75%

C67.5%

D20%

E65%

2

A randomized control double-blind study is conducted on the efficacy of 2 sulfonylureas. The study concluded that medication 1 was more efficacious in lowering fasting blood glucose than medication 2 (p ≤ 0.05; 95% CI: 14 [10-21]). Which of the following is true regarding a 95% confidence interval (CI)?

AIf the same study were repeated multiple times, approximately 95% of the calculated confidence intervals would contain the true population parameter.

BThe 95% confidence interval is the probability chosen by the researcher to be the threshold of statistical significance.

CWhen a 95% CI for the estimated difference between groups contains the value ‘0’, the results are significant.

DIt represents the probability that chance would not produce the difference shown, 95% of the time.

EThe study is adequately powered at the 95% confidence interval.

3

A researcher is trying to determine whether a newly discovered substance X can be useful in promoting wound healing after surgery. She conducts this study by enrolling the next 100 patients that will be undergoing this surgery and separating them into 2 groups. She decides which patient will be in which group by using a random number generator. Subsequently, she prepares 1 set of syringes with the novel substance X and 1 set of syringes with a saline control. Both of these sets of syringes are unlabeled and the substances inside cannot be distinguished. She gives the surgeon performing the surgery 1 of the syringes and does not inform him nor the patient which syringe was used. After the study is complete, she analyzes all the data that was collected and performs statistical analysis. This study most likely provides which level of evidence for use of substance X?

ALevel 3

BLevel 1

CLevel 4

DLevel 5

ELevel 2

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