Chapter·BiochemistryMetabolism

Fed state vs. fasting state metabolismDownloads

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Sample Questions

1

A 24-year-old man presents for an annual check-up. He is a bodybuilder and tells you he is on a protein-rich diet that only allows for minimal carbohydrate intake. His friend suggests he try exogenous glucagon to help him lose some excess weight before an upcoming competition. Which of the following effects of glucagon is he attempting to exploit?

AIncreased glucose utilization by tissues

BDecreased blood cholesterol level

CIncreased hepatic gluconeogenesis

DIncreased lipolysis in adipose tissues

EIncreased hepatic glycogenolysis

2

A 45-year-old woman with type 1 diabetes mellitus is brought to the emergency department by her husband because of polyuria, nausea, vomiting, and altered mental status for 4 hours. On arrival, she is unconscious. Treatment with a drug is begun that increases glucose transport to skeletal muscle and adipose tissue. Which of the following cellular events is most likely to also occur in response to this drug?

ADephosphorylation of fructose-1,6-bisphosphatase

BIncreased activity of acyl-CoA dehydrogenases

CCleavage of UDP from UDP-glucose

DUpregulation of glucose transporter type 3 expression

EPhosphorylation of glycogen phosphorylase kinase

3

A 55-year-old man with alcoholic cirrhosis is admitted to the hospital for routine evaluation before liver transplantation. The physician asks the patient to stop eating 10 hours before surgery. Which of the following structures contributes directly to preventing fasting hypoglycemia by producing glucose in this patient?

AAdrenal cortex

BSkeletal muscle

CRed blood cells

DSkin

EIntestine

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