A new mother expresses her concerns because her 1-day-old newborn has been having feeding difficulties. The child vomits after every feeding and has had a continuous cough since shortly after birth. The mother denies any greenish coloration of the vomit and says that it is only composed of whitish milk that the baby just had. The child exhibits these coughing spells during the exam, at which time the physician notices the child’s skin becoming cyanotic. The mother states that the child was born vaginally with no complications, although her records show that she had polyhydramnios during her last ultrasound before the delivery. Which of the following is the most likely cause of the patient’s symptoms?
AFailure of recanalization of duodenum
BObstruction due to failure of rotation of pancreatic tissue
CHypertrophy of the pyloric sphincter
DFailure of neural crest cells to migrate into the myenteric plexus
EDefective formation of the esophagus with tracheoesophageal connection
A 4-week-old infant is brought to the emergency department by his parents with violent vomiting. It started about 3 days ago and has slowly gotten worse. He vomits after most feedings but seems to keep some formula down. His mother notes that he is eager to feed between episodes and seems to be putting on weight. Other than an uncomplicated course of chlamydia conjunctivitis, the infant has been healthy. He was born at 39 weeks gestation via spontaneous vaginal delivery. He is up to date on all vaccines and is meeting all developmental milestones. The physical exam is significant for a palpable mass in the right upper quadrant. What is the first-line confirmatory diagnostic test and associated finding?
AAbdominal ultrasound; elongated pyloric channel and muscle hypertrophy
BBarium upper GI series; GE junction and portion of the stomach in thorax
CAir enema; filling defect and coil spring sign
DBarium upper GI series; bird beak sign and corkscrewing
EAbdominal X-ray; ‘double bubble’ sign
A 43-year-old man visits his physician’s office for a routine check-up. He tells his physician that he is otherwise healthy, except for persistent headaches that he gets every morning. Upon further questioning, he reveals that he has been changing glove sizes quite frequently over the past couple of years. His wedding ring doesn’t fit him anymore. He thought this was probably due to some extra weight that he has put on. Vital signs include: blood pressure 160/90 mm Hg, heart rate 82/min, and respiratory rate 21/min. His current physical appearance is cataloged in the image. His past medical history is significant for diabetes for which he has been receiving treatment for the past 2 years. Which of the following organs most likely has a structural abnormality that has resulted in this patient’s current presentation?
ALiver
BPancreas
CPosterior pituitary gland
DLungs
EAnterior pituitary gland
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