A 30-year-old man comes to the physician for a follow-up examination 1 month after sustaining a chemical burn over the dorsum of his right hand and forearm. Physical examination shows hyperextension of the hand at the wrist. The skin over the dorsum of the wrist is tense and there is a thick, epithelialized scar. Range of motion of the right wrist is restricted. This patient's contracture is most likely due to activity of which of the following cells?
AFibroblasts
BMyofibroblasts
CNeutrophils
DMacrophages
EEndothelial cells
A 15-year-old boy presents with shortness of breath on exertion for the past 2 weeks. Although he does not have any other complaints, he is concerned about not gaining much weight despite a good appetite. His height is 188 cm (6 ft 2 in) and weight is 58 kg (124 lb). His blood pressure is 134/56 mm Hg and his pulse rate is 78/min. On cardiac auscultation, his apex beat is displaced laterally with a diastolic murmur lateral to the left sternal border. Slit-lamp examination shows an upward and outward displacement of both lenses. Synthesis of which of the following proteins is most likely defective in this patient?
AFibronectin
BElastin
CFibrillin
DReticular fibers
ELaminin
A 15-year-old female presents to her family physician for an annual school physical exam and check-up. She is accompanied by her mother to the visit and is present in the exam room. The patient has no complaints, and she does not have any past medical problems. She takes no medications. The patient reports that she remains active, exercising 5 times a week, and eats a healthy and varied diet. Which of the following would be the best way for the physician to obtain a more in-depth social history, including sexual history and use of alcohol, tobacco, or recreational drugs?
ADisallow the mother to be present in the examination room throughout the entirety of the visit
BGive the patient a social history questionnaire to fill out in the exam room
CAsk the mother to step outside into the hall for a portion of the visit
DAsk the patient the questions directly, with her mother still in the exam room
ESpeak softly to the patient so that the mother does not hear and the patient is not embarrassed
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