A 49-year-old man presents with progressive weakness in his arms and legs over 24 months. He has bulbar symptoms including dysphagia and dysarthria. EMG shows widespread denervation. What is the most important prognostic factor?
AAge at onset
BRate of progression
CBulbar involvement
DSite of onset
EFamily history
A 28-year-old woman presents with sudden onset severe headache during exercise. She vomits and has neck stiffness. CT head shows subarachnoid hemorrhage. What is the most likely cause?
AArteriovenous malformation
BBerry aneurysm
CCarotid dissection
DHypertensive hemorrhage
ETrauma
A 41-year-old man presents with progressive weakness in his hands and arms over 12 months. He has muscle fasciculations and hyperreflexia. EMG shows both acute and chronic denervation changes. What is the prognosis?
AExcellent with treatment
BGood with supportive care
CVariable depending on subtype
DPoor with 3-5 year survival
EStable with medication
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