Chapter·PhysiologyGeneral Physiology

Signal Transduction MechanismsDownloads

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Sample Questions

1

Which of the following statements best describes the mechanism of action of insulin on target cells?

AInsulin binds to a receptor on the outer surface of the plasma membrane, activating adenylate cyclase through the Gs protein.

BInsulin binds to a cytoplasmic receptor and is transferred as a hormone receptor complex to the nucleus to modulate gene expression.

CInsulin enters the cell and causes the release of calcium ions from intracellular stores.

DInsulin binds to a transmembrane receptor on the outer surface of the plasma membrane, activating the tyrosine kinase in the cytosolic domain of the receptor.

2

All the following hormones have receptors on the plasma membrane of target tissues except:

AEpinephrine

BGlucagon

CEstradiol

DThyrotropin

3

A primigravida at 38 weeks of gestation has gone into labor. Oxytocin was started to augment labor. The second messenger system through which oxytocin acts is:

ATyrosine kinase

BPhospholipase C (IP3/DAG pathway)

CcGMP

DcAMP

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