A patient given digoxin started having side effects like nausea and vomiting. The serum concentration of digoxin was 4 ng/mL. The plasma therapeutic range is 1-2 ng/mL. If the half-life of digoxin is 40 hours, how long should one wait before resuming the treatment?
A120 hours
B140-180 hours
C1 half-life (40 hours)
D80 hours
Drug X has an affinity for albumin, while drug Y has 150 times greater affinity. Which of the following statements is MOST accurate?
ADrug X will be more available in tissues
BDrug Y will be less available in tissues
CToxicity of drug Y may be influenced by multiple factors, not just its binding.
DThe free concentration of drug X in blood is higher, facilitating tissue distribution.
Which of the following drugs is known to have low first pass metabolism?
ALidocaine
BPropranolol
CTheophylline
DMorphine
+ 7 more in the PDF
Browse all chapters