Which of the following statements is true regarding competitive reversible antagonism?
AED50 remains unchanged in competitive reversible antagonism.
BEfficacy and Vmax remain unchanged.
CPotency remains unchanged in the presence of a competitive antagonist.
DAffinity (Kd) remains unchanged in competitive reversible antagonism.
A factor that is likely to increase the duration of action of a drug that is partially metabolized by CYP3A4 in the liver is:
AChronic administration of phenobarbital with the drug
BDisplacement from tissue binding sites by another drug
CChronic administration of rifampicin
DChronic administration of cimetidine with the drug
A patient on warfarin has a high INR. Which drug likely caused this?
AAmiodarone
BPhenytoin
CCarbamazepine
DRifampicin
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