The diagnosis of myasthenia gravis is made by a positive edrophonium test, repetitive nerve stimulation test of a weak muscle, and anti-acetylcholine receptor antibody assay. MRI of the mediastinum is now indicated to:
ARule out thymoma
BLook for small cell carcinoma and Lambert-Eaton syndrome
CRule out sarcoidosis
DRule out tuberculosis before starting prednisone
The mechanism of action of botulinum toxin primarily involves disruption of:
AMuscle transmission
BNon-neuromuscular transmission
CNeuromuscular transmission
DNeural transmission
Sequence the events in neuromuscular action potential conduction: 1. Sodium channels open in the end plate 2. Calcium enters at the nerve terminal 3. Release of acetylcholine
A$1 \rightarrow 2 \rightarrow 3$
B$1 \rightarrow 3 \rightarrow 2$
C$3 \rightarrow 2 \rightarrow 1$
D$2 \rightarrow 3 \rightarrow 1$
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