In the context of myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML), which of the following cytogenetic abnormalities is associated with the worst prognosis?
Ainv(16)
BNormal cytogenetics
CMonosomy 7
Dt(8;21) translocation
All of the following are good prognostic factors for pediatric acute lymphoblastic leukemia, except:
AHyperdiploidy
BCNS disease at diagnosis
Ct(12;21)
DInitial WBC count <50,000/cumm
What is the most common type of acute myeloid leukemia in patients with Down's syndrome?
AAcute megakaryoblastic leukemia M7
BAcute myeloid leukemia M1
CAcute promyelocytic leukemia M3
DAcute myeloid leukemia M2
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