Chapter·BiochemistryGenetic Disorders and Biochemical Pathology

HemoglobinopathiesDownloads

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Sample Questions

1

Which of the following is the most sensitive and specific test during antenatal check-up for a pregnant lady with family history of Thalassemia?

AP. smear and reticulocyte count

BHemoglobin electrophoresis

CHigh performance liquid chromatography

DNESTROFT

2

An 18-year-old man recently diagnosed with beta-thalassemia minor has a hemoglobin level of 10.5 g/dL and feels well. Which of the following findings is characteristic of this condition?

Aan increased amount of fetal hemoglobin (HbF) and hemoglobin A2 (HbA2)

Bincreased osmotic fragility of red blood cells

Cnormal bone marrow iron stores

Dincreased macroglobulins in the serum

3

A 25-year-old lady presented with anemia, jaundice, and recurrent joint pains. All of the following are true except:

AHbA will be undetectable

BShe may have retinopathy

CHydroxyurea would help her

DShe can present with pulmonary bleeds

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