Which of the following statements best describes the mechanism of action of insulin on target cells?
AInsulin binds to a receptor on the outer surface of the plasma membrane, activating adenylate cyclase through the Gs protein.
BInsulin binds to a cytoplasmic receptor and is transferred as a hormone receptor complex to the nucleus to modulate gene expression.
CInsulin enters the cell and causes the release of calcium ions from intracellular stores.
DInsulin binds to a transmembrane receptor on the outer surface of the plasma membrane, activating the tyrosine kinase in the cytosolic domain of the receptor.
Hyperammonemia impairs the citric acid cycle by depleting which of the following?
APyruvate
BOxaloacetate
CSuccinate
Dα-ketoglutarate
What is the mechanism of cyanide poisoning?
AInhibition of cytochrome oxidase
BInhibition of complex I
CInhibition of cytochrome C
DInhibition of carbonic anhydrase
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