Chapter·BiochemistryDetoxification Pathways

Phase I Reactions: Cytochrome P450 SystemDownloads

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Sample Questions

1

The cytochrome involved in monooxygenase-mediated detoxification of drugs is:

ACyt P 450

BCytochrome b5

CCytochrome c

DCytochrome oxidase

2

Which drug should not be given with ketoconazole?

AIndinavir

BMacrolide

CAll of the options

DAminoglycoside

3

In the metabolism of xenobiotics, which of the following reactions does not occur in phase one?

AReduction

BHydrolysis

COxidation

DConjugation

+ 7 more in the PDF

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