Which enzyme deficiency leads to hyperhomocysteinemia?
APhenylalanine hydroxylase
BGlucose-6-phosphate dehydrogenase
CGalactose-1-phosphate uridyltransferase
DMethionine synthase
Ammonia causes depletion of which of the following in TCA cycle?
AMalate
BOxaloacetate
CAlpha-ketoglutarate
DFumarate
Hyperammonaemia inhibits the TCA cycle by depleting which of the following?
Asuccinate
Bα-ketoglutarate
Cmalate
Dfumarate
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