Which of the following drugs does not cause pharmacological adrenalectomy?
AMitotane
BMethotrexate
CKetoconazole
DAminoglutethimide
A 20-year-old woman with a family history of von Willebrand disease is found to have an activated partial thromboplastin time (aPTT) of 78 (normal = 32) on routine testing prior to cholecystectomy. Further investigation reveals a prothrombin time (PT) of 13 (normal = 12), a platelet count of 350,000/mm³, and an abnormal bleeding time. Which of the following should be administered in the perioperative period?
AFactor VIII
BDesmopressin (DDAVP)
CPlatelets
DVitamin K
In extraction, the best time to administer analgesics is:
APrior to the procedure
BAfter anaesthesia has worn off
CWhen pain is moderate to severe
DJust before anaesthesia wears off
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