Chapter·PharmacologyAntimicrobial Agents

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Sample Questions

1

Which of the following is NOT a mechanism of antibiotic resistance?

AEfflux pump activity

BInactivation by enzymes such as beta-lactamase

CModification of drug target sites

DIncreased drug absorption

2

What is the mechanism of action of aminoglycoside antibiotics?

AInhibition of protein synthesis

BInhibition of DNA replication

CDisruption of the cell membrane

DInhibition of bacterial cell wall synthesis

3

What is the mechanism of resistance in MRSA?

APBP2a alteration

BEfflux pump activation

CPorins modification

DBeta-lactamase production

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