Chapter·PhysiologyChronobiology and Circadian Rhythms

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Sample Questions

1

The cytochrome involved in monooxygenase-mediated detoxification of drugs is:

ACyt P 450

BCytochrome b5

CCytochrome c

DCytochrome oxidase

2

Match the following antiarrhythmic drugs with their mechanism of action: | Mechanism of action | Drug | | :-- | :-- | | 1. Na+ channel blocker | A. Quinidine | | 2. K+ channel blocker | B. Digoxin | | 3. Na+K+ ATPase inhibitor | C. Esmolol | | 4. Beta-blocker | D. Ibutilide |

A1-D, 2-B, 3-A, 4-C

B1-A, 2-D, 3-B, 4-C

C1-A, 2-C, 3-D, 4-B

D1-D, 2-C, 3-A, 4-B

3

Which of the following drugs should be given in a sustained-release oral dosage form?

AAn anti-arrhythmic drug with a plasma half life of 10 seconds used for acute treatment of PSVT

BAnti inflammatory drugs with the plasma half life of 24 hours

CHypnotic drugs with a plasma half life of 2 hours

DAn antihypertensive with a plasma half-life of 3 hours

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