Chapter·PharmacologyDrugs in Psychiatric Disorders

Antidepressants: SSRIs and SNRIsDownloads

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1

An SSRI antidepressant, such as fluoxetine, will be prescribed for an adult patient. You should advise him or her that two of the most likely side effects or adverse responses that may eventually occur at therapeutic blood levels are which of the following?

ASexual dysfunction and sleep disturbances

BSexual dysfunction and nausea

CHeadache and diarrhea

DTremor and weight gain

2

How do SSRIs alleviate symptoms of depression?

ABy increasing synaptic serotonin levels

BBy inhibiting GABA receptors

CBy increasing norepinephrine degradation

DBy decreasing dopamine release

3

What are the primary mechanisms behind cardiac toxicity associated with Tricyclic antidepressants?

ANorepinephrine reuptake inhibition only

BAnticholinergic effects on the heart

CBoth norepinephrine reuptake inhibition and anticholinergic effects on the heart

DDirect membrane stabilizing effects only

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