A 3-year-old boy is found to have spontaneous bursts of non-rhythmic conjugate eye movements in various directions, as well as hypotonia and myoclonus. Physical examination also reveals an abdominal mass. A CT scan shows a mass in the adrenal gland. Which of the following statements is false regarding the patient's condition?
AImmunohistochemical detection of chromogranin is not useful for diagnosis.
B70-80% of tumors are associated with elevated production of catecholamines.
CRearrangement or deletion of short arm of chromosome 1 is seen in 25-35% of cases.
DThe most common site of tumor is adrenal medulla.
In a patient diagnosed with pheochromocytoma, what is the appropriate preoperative pharmacological management to control hypertension before surgery?
APhenoxybenzamine and propranolol
BPropranolol
CNitroglycerine
DPhentolamine
Which of the following is best for diagnosis of pheochromocytoma?
A24-hour Urinary Hydroxy indole acetic acid
B24-hour urinary Vanillyl Mandelic acid
C24-hour Urinary Hydroxy tryptamine
D24-hour urinary Fractionated Metanephrine
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