Chapter·BiochemistryMolecular Biology and Genomics

DNA Fingerprinting and ForensicsDownloads

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Sample Questions

1

Which of the following techniques can be used to detect single base pair substitutions?

AFISH

BSouthern blot

CPCR

DRestriction Fragment Length Polymorphism (RFLP)

2

Which of the following is the least suitable source for DNA extraction?

ACSF

BHair roots

CSemen

DBuccal mucosa

3

DNA fingerprinting is used for paternity testing and forensic identification of suspects. Which of the following is the most accurate description of DNA fingerprinting?

ADNA is isolated from blood, skin, or sperm and its fragment size distribution is analyzed by gel electrophoresis

BDNA can be isolated from blood, skin, or sperm and analyzed for variable patterns of restriction fragments arising from tandemly repeated sequences (microsatellites)

CDNA is isolated from blood, skin, or sperm and hybridized with probes from the HLA locus to visualize HLA gene patterns

DDNA is copied from blood, skin, or sperm RNA using reverse transcriptase and analyzed for the pattern of complementary DNAs

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