Activated protein C inhibits the clotting mechanism by inactivating which of the following clotting factors?
AFactor Va and Factor VIIIa
BFactor III and Factor VIIIa
CFactor VIIIa and Factor IX
DFactor Va and Factor VII
Von Willebrand disease involves a deficiency of which factor?
ADefect in platelet adhesion due to von Willebrand factor deficiency
BDefect in fibrin formation affecting clot stabilization
CGeneralized defects involving small blood vessels
DDefect in clotting factors affecting secondary hemostasis
Which of the following statements is true regarding von Willebrand disease?
AFactor VIII levels are always normal.
BPlatelet count is consistently decreased.
CBleeding time is prolonged due to impaired platelet adhesion.
DActivated partial thromboplastin time (aPTT) is always normal.
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