Chapter·PhysiologyEndocrinology

Pancreatic Hormones and Glucose MetabolismDownloads

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Sample Questions

1

Increased insulin is characterized by all of the following, except:

AHypoglycemia

BEnhanced fatty acid synthesis

CIncreased Intracellular potassium

DIncreased Glucagon secretion

2

The diagnosis of diabetes mellitus is certain in which of the following situations?

AAbnormal oral glucose tolerance in a 24-yrs-old woman who has been dieting

BA serum glucose level >7.8 mmol/L in a woman in her twenty-fifth week of gestation after a 50-g oral glucose load

CPersistent asymptomatic glycosuria in a 30-yrs-old woman

DSuccessive fasting plasma glucose concentrations of 8, 9, and 8.5 mmol/L in an asymptomatic, otherwise healthy individual.

3

Which of the following statements best describes the mechanism of action of insulin on target cells?

AInsulin binds to a receptor on the outer surface of the plasma membrane, activating adenylate cyclase through the Gs protein.

BInsulin binds to a cytoplasmic receptor and is transferred as a hormone receptor complex to the nucleus to modulate gene expression.

CInsulin enters the cell and causes the release of calcium ions from intracellular stores.

DInsulin binds to a transmembrane receptor on the outer surface of the plasma membrane, activating the tyrosine kinase in the cytosolic domain of the receptor.

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