Volume of distribution of a drug is 500 ml and target concentration of drug in blood is 5 g/L. 20% of administered drug is reached to systemic circulation. What will be the loading dose of that drug -
A1 gm
B5 gm
C25 gm
D12.5 gm
Which of the following factors influences the duration of action of a drug?
ABioavailability
BClearance
CRate of elimination
DAll of the options
Which route of administration undergoes the maximum first pass metabolism?
AIntra-arterial
BRectal
COral
DIntravenous
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