Which among the following is the false statement regarding statins?
AThese drugs should not be stopped even in severe conditions like injury, surgery etc.
BAlthough HMG-CoA reductase inhibitors substantially reduce the risk of cardiovascular events, there is mild increase in lipoprotein a (Lpa) levels.
CWith the long term use, there is slight increase in the incidence of type 2 diabetes mellitus.
DThey can be given with verapamil and other enzyme inhibitors
Which of the following is a characteristic of simvastatin?
ASpecific CYP3A4 substrate with high interaction potential
BDerived from fungal metabolite
CProdrug requiring hepatic activation
DShort half-life requiring evening dosing
Which of the following is not considered a pharmacogenetic condition?
AAdenosine deaminase deficiency
BCoumarin insensitivity
CG6PD deficiency
DMalignant hyperthermia
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