Chapter·PharmacologyGeneral Pharmacology

Pharmacokinetics: Metabolism and ExcretionDownloads

10Questions
10Flashcards
1Tables & Flowcharts

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Sample Questions

1

The cytochrome involved in monooxygenase-mediated detoxification of drugs is:

ACyt P 450

BCytochrome b5

CCytochrome c

DCytochrome oxidase

2

A patient given digoxin started having side effects like nausea and vomiting. The serum concentration of digoxin was 4 ng/mL. The plasma therapeutic range is 1-2 ng/mL. If the half-life of digoxin is 40 hours, how long should one wait before resuming the treatment?

A120 hours

B140-180 hours

C1 half-life (40 hours)

D80 hours

3

A substance has a clearance similar to inulin clearance. How is this substance primarily excreted in urine?

ATubular Secretion

BGlomerular filtration

CVascular leakage

DBoth tubular secretion and glomerular filtration

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