What is the best treatment option for a patient aged 65 years with severe aplastic anemia who has an HLA-compatible sibling available?
AAntithymocyte globulin followed by cyclosporine
BNon-myeloablative bone marrow transplantation from the HLA identical sibling
CCyclosporine monotherapy
DConventional myeloablative bone marrow transplantation from the HLA identical sibling
An 18-year-old male presents to the OPD with gum bleeding, fever, low total leukocyte count (TLC), and low platelet count. General examination is unremarkable. Further investigations reveal a low reticulocyte count, absent megakaryocytes, and no immature cells in the bone marrow. What is the most likely diagnosis?
AImmune Thrombocytopenic Purpura (ITP)
BMyelodysplastic Syndrome (MDS)
CAplastic anemia
DAcute Myeloid Leukemia (AML)
Which disease will show the mode of inheritance depicted in this pedigree?
AAchondroplasia
BPrader-Willi syndrome
CWilson disease
DWiskott-Aldrich syndrome
EHemophilia A
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