Chapter·OrthopaedicsMetabolic Bone Diseases

Osteomalacia and RicketsDownloads

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Sample Questions

1

A child presents with poor growth and swelling at joints. A radiograph of his wrist is given below. Lab investigations reveal serum ALP levels of >1500. What is the possible diagnosis?

ARickets

BOsteoporosis

COsteomalacia

DOsteogenesis imperfecta

2

The primary pharmacological intervention to retard avascular necrosis progression is?

AHigh-dose calcium supplementation

BVitamin D supplementation alone

CCorticosteroid therapy

DBisphosphonates (Alendronate)

3

A child presents with rachitic changes in the limbs that are not responding to Vitamin D supplementation. Investigations reveal the following results: - Calcium: $9.5 \mathrm{mg} / \mathrm{dl}$ - Phosphorus: $1.6 \mathrm{mg} / \mathrm{dl}$ - Alkaline phosphatase (ALP): 814 IU - Serum PTH: $24.2 \mathrm{pg} / \mathrm{ml}$ - Serum electrolytes, creatinine, and blood gases: Normal. What is the most likely diagnosis?

AHypophosphatemic rickets

BVitamin D-dependent rickets type 2

CVitamin D-dependent rickets type 1

DChronic renal failure

EVitamin D deficiency rickets

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