Chapter·BiochemistryVitamins and Coenzymes

Folate and Vitamin B12 in One-Carbon MetabolismDownloads

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Sample Questions

1

Gastric secretions are essential for absorption of -

ACobalamin

BFat

CThiamine

DFolic acid

2

Which of the following is a consequence of Vitamin B12 deficiency?

AEnhanced folate absorption

BIncreased red blood cell production

CDecreased metabolic intermediate levels

DNeurological complications

3

30 years old came with complaints of easy fatigability, exertional dyspnea, and weight loss. She also complains of frequent falls. physical examination revealed there was a bilateral decrease in vibration sense. Her hemoglobin levels were 8.2g%. She was treated with folate. Her anemia improved but neurological symptoms worsened. Which of the following is the most probable reason for her condition?

AFolate therapy caused rapid use of Vit B12 stores aggravating symptoms

BVitamin B6 deficiency unmasked by folate treatment.

CImpaired folate metabolism in the central nervous system.

DMalabsorption of folate due to gastrointestinal issues.

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