Which discovery in gene regulation was awarded the Nobel Prize in Physiology or Medicine in 2006?
ADiscovery of RNA interference (RNAi)
BRole of mitochondrial DNA in cellular functions
CInvolvement of lipoxins in inflammation
DFunction of transcription factors in gene regulation
During eukaryotic protein synthesis, phosphorylation of which of the following is enhanced by insulin?
AeIF2
BeIF4A
CeIF4G
DeIF4E
Which of the following statements best describes the mechanism of action of insulin on target cells?
AInsulin binds to a receptor on the outer surface of the plasma membrane, activating adenylate cyclase through the Gs protein.
BInsulin binds to a cytoplasmic receptor and is transferred as a hormone receptor complex to the nucleus to modulate gene expression.
CInsulin enters the cell and causes the release of calcium ions from intracellular stores.
DInsulin binds to a transmembrane receptor on the outer surface of the plasma membrane, activating the tyrosine kinase in the cytosolic domain of the receptor.
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