A child presents with recurrent chest infections and abdominal pain. There is a history of 1 blood transfusion in the past. On examination, he had icterus and mild splenomegaly. Electrophoresis shows increased HbA2, HbF, and S spike. What is the likely diagnosis?
AHbC disease
BSickle cell disease
CAplastic anemia
DSickle Beta Thalassemia
Which of the following statements is MOST accurate regarding cyanosis in methemoglobinemia?
AAlways associated with tachycardia
BCaused by increased carboxyhemoglobin levels
CDoes not improve with supplemental oxygen
DCan occur in both congenital and acquired forms of the disease.
Which of the following conditions is the classic example of acute intravascular hemolysis triggered by oxidative stress?
AHereditary spherocytosis
BSickle cell disease
CAcute G6PD deficiency
DNone of the options
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