Acetazolamide is given to a patient with angle closure glaucoma. It is a reversible competitive inhibitor of carbonic anhydrase enzyme. Which of the following should be the effect of this drug?
ANo change in Vmax
BIncrease in both Km and Vmax
CDecrease in Km
DDecrease in Vmax
Which of the following is an example of allosteric inhibition?
ADecreased synthesis of glucokinase by glucagon
BInactivation of glycogen synthase by phosphorylation
CInhibition of PFK-1 by citrate
DNone of the options
Which one of the following shows allosteric inhibition of glycolysis?
AAmino acid alanine
B2,3 BPG
CCitrate
DMalonic acid
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