Fourteen days after a laparoscopic cholecystectomy for cholelithiasis, a 45-year-old woman comes to the emergency department because of persistent episodic epigastric pain for 3 days. The pain radiates to her back, occurs randomly throughout the day, and is associated with nausea and vomiting. Each episode lasts 30 minutes to one hour. Antacids do not improve her symptoms. She has hypertension and fibromyalgia. She has smoked 1–2 packs of cigarettes daily for the past 10 years and drinks 4 cans of beer every week. She takes lisinopril and pregabalin. She appears uncomfortable. Her temperature is 37°C (98.6° F), pulse is 84/min, respirations are 14/min, and blood pressure is 127/85 mm Hg. Abdominal examination shows tenderness to palpation in the upper quadrants without rebound or guarding. Bowel sounds are normal. The incisions are clean, dry, and intact. Serum studies show:
AST 80 U/L
ALT 95 U/L
Alkaline phosphatase 213 U/L
Bilirubin, total 1.3 mg/dL
Direct 0.7 mg/dL
Amylase 52 U/L
Abdominal ultrasonography shows dilation of the common bile duct and no gallstones. Which of the following is the most appropriate next step in management?
Q52
A 45-year-old man undergoes a parathyroidectomy given recurrent episodes of dehydration and kidney stones caused by hypercalcemia secondary to an elevated PTH level. He is recovering on the surgical floor on day 3. His temperature is 97.6°F (36.4°C), blood pressure is 122/81 mmHg, pulse is 84/min, respirations are 12/min, and oxygen saturation is 98% on room air. The patient is complaining of perioral numbness currently. What is the most appropriate management of this patient?
Q53
A 40-year-old woman was admitted to the surgical service after an uncomplicated appendectomy. She underwent surgery yesterday and had an uneventful postoperative course. However, she now complains that she is unable to completely void. She also complains of pain in the suprapubic area. You examine her and confirm the tenderness and fullness in the suprapubic region. You ask the nurse to perform a bladder scan, which reveals 450cc. What is the next appropriate step in management?
Q54
A 42-year-old woman presents to the physician because of an abnormal breast biopsy report following suspicious findings on breast imaging. Other than being concerned about her report, she feels well. She has no history of any serious illnesses and takes no medications. She does not smoke. She consumes wine 1–2 times per week with dinner. There is no significant family history of breast or ovarian cancer. Vital signs are within normal limits. Physical examination shows no abnormal findings. The biopsy shows lobular carcinoma in situ (LCIS) in the left breast. Which of the following is the most appropriate next step in management?
Q55
A 50-year-old obese woman presents for a follow-up appointment regarding microcalcifications found in her left breast on a recent screening mammogram. The patient denies any recent associated symptoms. The past medical history is significant for polycystic ovarian syndrome (PCOS), for which she takes metformin. Her menarche occurred at age 11, and the patient still has regular menstrual cycles. The family history is significant for breast cancer in her mother at the age of 72. The review of systems is notable for a 6.8 kg (15 lb) weight loss in the past 2 months. The vital signs include: temperature 37.0°C (98.6°F), blood pressure 130/70 mm Hg, pulse 82/min, respiratory rate 17/min, and oxygen saturation 98% on room air. On physical examination, the patient is alert and cooperative. The breast examination reveals no palpable masses, lymphadenopathy, or evidence of skin retraction. A biopsy of the left breast is performed, and histologic examination demonstrates evidence of non-invasive malignancy. Which of the following is the most appropriate definitive treatment for this patient?
Q56
One week after undergoing sigmoidectomy with end colostomy for complicated diverticulitis, a 67-year-old man has upper abdominal pain. During the surgery, he was transfused two units of packed red blood cells. His postoperative course was uncomplicated. Two days ago, he developed fever. He is currently receiving parenteral nutrition through a central venous catheter. He has type 2 diabetes mellitus, hypertension, and hypercholesterolemia. He is oriented to person, but not to place and time. Prior to admission, his medications included metformin, valsartan, aspirin, and atorvastatin. His temperature is 38.9°C (102.0°F), pulse is 120/min, and blood pressure is 100/60 mmHg. Examination shows jaundice of the conjunctivae. Abdominal examination shows tenderness to palpation in the right upper quadrant. There is no rebound tenderness or guarding; bowel sounds are hypoactive. Laboratory studies show:
Leukocytes 13,500 /mm3
Segmented neutrophils 75 %
Serum
Aspartate aminotransferase 140 IU/L
Alanine aminotransferase 85 IU/L
Alkaline phosphatase 150 IU/L
Bilirubin
Total 2.1 mg/dL
Direct 1.3 mg/dL
Amylase 20 IU/L
Which of the following is the most likely diagnosis in this patient?
Q57
A 23-year-old woman presents to her primary care physician for knee pain. The patient states it started yesterday and has been steadily worsening. She recently joined a volleyball team to try to get into shape as she was informed that weight loss would be beneficial for her at her last physical exam. She states that she has been repetitively pivoting and twisting on her knee while playing volleyball. The patient has a past medical history of polycystic ovarian syndrome and is currently taking oral contraceptive pills. Her temperature is 98.5°F (36.9°C), blood pressure is 137/88 mmHg, pulse is 90/min, respirations are 12/min, and oxygen saturation is 98% on room air. Physical exam reveals an obese woman with facial hair. Physical exam is notable for tenderness that is elicited with palpation over the medial aspect of the tibia just inferior to the patella. Her BMI is 37 kg/m^2. The rest of the exam of the lower extremity is not remarkable. Which of the following is the most likely diagnosis?
Q58
Five days after undergoing right knee arthroplasty for osteoarthritis, a 68-year-old man has severe pain in his right knee preventing him from participating in physical therapy. On the third postoperative day when the dressing was changed, the surgical wound appeared to be intact, slightly swollen, and had a clear secretion. He has a history of diabetes, hyperlipidemia, and hypertension. Current medications include metformin, enalapril, and simvastatin. His temperature is 37.3°C (99.1°F), pulse is 94/min, and blood pressure is 130/88 mm Hg. His right knee is swollen, erythematous, and tender to palpation. There is pain on movement of the joint. The medial parapatellar skin incision appears superficially opened in its proximal and distal part with yellow-green discharge. There is blackening of the skin on both sides of the incision. Which of the following is the next best step in the management of this patient?
Post-op care US Medical PG Practice Questions and MCQs
Question 51: Fourteen days after a laparoscopic cholecystectomy for cholelithiasis, a 45-year-old woman comes to the emergency department because of persistent episodic epigastric pain for 3 days. The pain radiates to her back, occurs randomly throughout the day, and is associated with nausea and vomiting. Each episode lasts 30 minutes to one hour. Antacids do not improve her symptoms. She has hypertension and fibromyalgia. She has smoked 1–2 packs of cigarettes daily for the past 10 years and drinks 4 cans of beer every week. She takes lisinopril and pregabalin. She appears uncomfortable. Her temperature is 37°C (98.6° F), pulse is 84/min, respirations are 14/min, and blood pressure is 127/85 mm Hg. Abdominal examination shows tenderness to palpation in the upper quadrants without rebound or guarding. Bowel sounds are normal. The incisions are clean, dry, and intact. Serum studies show:
AST 80 U/L
ALT 95 U/L
Alkaline phosphatase 213 U/L
Bilirubin, total 1.3 mg/dL
Direct 0.7 mg/dL
Amylase 52 U/L
Abdominal ultrasonography shows dilation of the common bile duct and no gallstones. Which of the following is the most appropriate next step in management?
A. Counseling on alcohol cessation
B. Endoscopic retrograde cholangiopancreatography (Correct Answer)
C. Proton pump inhibitor therapy
D. CT scan of the abdomen
E. Reassurance and follow-up in 4 weeks
Explanation: ***Endoscopic retrograde cholangiopancreatography***
- The patient's symptoms (epigastric pain radiating to the back, nausea, vomiting, elevated liver enzymes, and **common bile duct (CBD) dilation** on ultrasound after cholecystectomy) are highly suggestive of **postcholecystectomy syndrome**, specifically due to a retained or de novo **CBD stone** or **sphincter of Oddi dysfunction**.
- **ERCP** is both diagnostic and therapeutic in this setting, allowing for visualization of the bile ducts, stone extraction (if present), or sphincterotomy.
*Counseling on alcohol cessation*
- While **alcohol cessation** is beneficial for overall health, especially with a history of alcohol use, it is not the most immediate or appropriate next step for the acute and severe symptoms presented.
- The patient's symptoms are more indicative of a **biliary obstruction** rather than alcohol-related chronic pancreatitis or liver disease, given the acute onset post-surgery.
*Proton pump inhibitor therapy*
- **PPI therapy** is used for acid-related disorders such as GERD or peptic ulcers, which typically present with burning epigastric pain that improves with antacids.
- This patient's pain radiates to the back, is associated with nausea and vomiting, does not improve with antacids, and has abnormal imaging/labs (CBD dilation, elevated liver enzymes), ruling out a simple acid-related issue.
*CT scan of the abdomen*
- An abdominal **CT scan** could provide more detailed imaging but is generally less effective than ERCP for evaluating **biliary duct pathology** and is not therapeutic.
- Given the ultrasound findings of **CBD dilation** and the patient's symptoms, a more invasive but definitive diagnostic and therapeutic procedure is warranted.
*Reassurance and follow-up in 4 weeks*
- The patient is experiencing severe, persistent symptoms with abnormal liver enzymes and imaging findings indicating **biliary obstruction** post-cholecystectomy.
- **Reassurance and delayed follow-up** would be inappropriate and could lead to worsening of her condition, including cholangitis or pancreatitis if left untreated.
Question 52: A 45-year-old man undergoes a parathyroidectomy given recurrent episodes of dehydration and kidney stones caused by hypercalcemia secondary to an elevated PTH level. He is recovering on the surgical floor on day 3. His temperature is 97.6°F (36.4°C), blood pressure is 122/81 mmHg, pulse is 84/min, respirations are 12/min, and oxygen saturation is 98% on room air. The patient is complaining of perioral numbness currently. What is the most appropriate management of this patient?
A. Potassium
B. TSH level
C. Vitamin D
D. Observation
E. Calcium gluconate (Correct Answer)
Explanation: ***Calcium gluconate***
- The patient's presentation of **perioral numbness** following a parathyroidectomy, especially given a history of hypercalcemia, is highly suggestive of **hypocalcemia**.
- **Calcium gluconate** is indicated for acute symptomatic hypocalcemia to rapidly raise serum calcium levels and alleviate symptoms.
*Potassium*
- There is no clinical indication for **potassium** supplementation; the symptom of perioral numbness is not associated with potassium imbalance.
- Parathyroidectomy and hypercalcemia primarily affect calcium and phosphate metabolism, not typically potassium.
*TSH level*
- A **TSH level** is used to assess thyroid function, which is generally not directly affected by parathyroidectomy unless thyroid tissue was incidentally damaged.
- The symptoms presented do not suggest a thyroid dysfunction.
*Vitamin D*
- While **vitamin D** is crucial for calcium absorption and might be used in chronic management of hypocalcemia, it would not provide the immediate relief needed for acute symptomatic hypocalcemia.
- Acute symptoms like perioral numbness require a rapid elevation of serum calcium.
*Observation*
- **Observation** is inappropriate given the patient's symptomatic presentation of **perioral numbness**, which indicates acute and potentially worsening hypocalcemia.
- Untreated symptomatic hypocalcemia can progress to more severe complications such as seizures, arrhythmias, and laryngospasm.
Question 53: A 40-year-old woman was admitted to the surgical service after an uncomplicated appendectomy. She underwent surgery yesterday and had an uneventful postoperative course. However, she now complains that she is unable to completely void. She also complains of pain in the suprapubic area. You examine her and confirm the tenderness and fullness in the suprapubic region. You ask the nurse to perform a bladder scan, which reveals 450cc. What is the next appropriate step in management?
A. Catheterization (Correct Answer)
B. Oral bethanechol chloride
C. Neostigmine methylsulfate injection
D. Intravenous furosemide
E. Intravenous neostigmine methylsulfate
Explanation: **Catheterization**
- The patient is presenting with **acute urinary retention**, confirmed by the inability to void, suprapubic pain, and a bladder scan showing 450cc, which exceeds the typical threshold for intervention (often 200-300cc).
- **Immediate catheterization** (usually Foley catheterization) is necessary to drain the bladder, relieve discomfort, and prevent complications like bladder distension injury or hydronephrosis.
*Oral bethanechol chloride*
- Bethanechol is a **cholinergic agonist** used to stimulate bladder contraction in cases of hypotonic bladder, but it is not appropriate for acute, complete urinary retention requiring immediate drainage.
- Its onset of action is too slow for the urgency of acute retention, and it would not resolve the immediate discomfort or risk of bladder damage.
*Neostigmine methylsulfate injection*
- Neostigmine is an **acetylcholinesterase inhibitor** that increases acetylcholine levels, potentially improving bladder contractility, but it is not typically the first-line treatment for acute postoperative urinary retention.
- Like bethanechol, it doesn't provide the rapid relief of bladder distension that catheterization does and is more often considered for chronic or neurogenic bladder dysfunction once acute retention is managed.
*Intravenous furosemide*
- Furosemide is a **loop diuretic** that increases urine production, which would exacerbate the problem in a patient with acute urinary retention.
- Increasing urine output without the ability to void would worsen bladder distension and patient discomfort, making it a contraindicated intervention.
*Intravenous neostigmine methylsulfate*
- While neostigmine can be given intravenously, its use in acute postoperative urinary retention is **not a primary treatment**.
- Its effect is slower than direct bladder drainage, and the immediate priority is to decompress the bladder to relieve symptoms and prevent complications.
Question 54: A 42-year-old woman presents to the physician because of an abnormal breast biopsy report following suspicious findings on breast imaging. Other than being concerned about her report, she feels well. She has no history of any serious illnesses and takes no medications. She does not smoke. She consumes wine 1–2 times per week with dinner. There is no significant family history of breast or ovarian cancer. Vital signs are within normal limits. Physical examination shows no abnormal findings. The biopsy shows lobular carcinoma in situ (LCIS) in the left breast. Which of the following is the most appropriate next step in management?
A. Careful observation + routine mammography (Correct Answer)
B. Left mastectomy + axillary dissection + local irradiation
C. Lumpectomy + routine screening
D. Lumpectomy + breast irradiation
E. Breast irradiation + tamoxifen
Explanation: ***Careful observation + routine mammography***
- **Lobular carcinoma in situ (LCIS)** is considered a **non-obligate precursor** to invasive carcinoma, meaning it indicates an increased risk for developing invasive breast cancer in either breast (approximately 1-2% per year), but it is not itself invasive.
- Management typically involves **careful surveillance** with routine clinical exams and **mammography**, as this is the most appropriate initial approach for classic LCIS.
- Surgical excision is often unnecessary due to LCIS's diffuse nature and the fact that it serves as a risk marker rather than a direct precancerous lesion requiring removal.
*Left mastectomy + axillary dissection + local irradiation*
- This aggressive approach is reserved for **invasive breast cancer** and would be excessive for LCIS, which is a non-invasive lesion and a marker of increased risk rather than an immediate threat.
- **Axillary dissection** is performed to stage nodal involvement in invasive cancer, which is not applicable here as LCIS does not metastasize.
*Lumpectomy + routine screening*
- While a **lumpectomy (excision)** may be considered for **pleomorphic LCIS** or when there is diagnostic uncertainty, it is not the standard initial management for classic LCIS.
- Classic LCIS is often multifocal and bilateral, making localized excision less effective as a risk-reduction strategy.
*Lumpectomy + breast irradiation*
- **Radiation therapy** is typically used to reduce local recurrence risk after **lumpectomy for invasive breast cancer** or **ductal carcinoma in situ (DCIS)**.
- For LCIS, irradiation is generally not recommended as it is non-invasive and does not benefit from local radiation treatment.
*Breast irradiation + tamoxifen*
- **Tamoxifen** is a selective estrogen receptor modulator (SERM) that can be **offered for risk reduction** in women with LCIS, potentially reducing the risk of invasive breast cancer by approximately 50%.
- However, tamoxifen is typically discussed as an **additional preventive option** after initial diagnosis and counseling, not as the immediate next step.
- **Breast irradiation** is not indicated for LCIS, as it is non-invasive and does not require local radiation treatment, making this combination inappropriate.
Question 55: A 50-year-old obese woman presents for a follow-up appointment regarding microcalcifications found in her left breast on a recent screening mammogram. The patient denies any recent associated symptoms. The past medical history is significant for polycystic ovarian syndrome (PCOS), for which she takes metformin. Her menarche occurred at age 11, and the patient still has regular menstrual cycles. The family history is significant for breast cancer in her mother at the age of 72. The review of systems is notable for a 6.8 kg (15 lb) weight loss in the past 2 months. The vital signs include: temperature 37.0°C (98.6°F), blood pressure 130/70 mm Hg, pulse 82/min, respiratory rate 17/min, and oxygen saturation 98% on room air. On physical examination, the patient is alert and cooperative. The breast examination reveals no palpable masses, lymphadenopathy, or evidence of skin retraction. A biopsy of the left breast is performed, and histologic examination demonstrates evidence of non-invasive malignancy. Which of the following is the most appropriate definitive treatment for this patient?
A. Tamoxifen
B. Observation with bilateral mammograms every 6 months
C. Lumpectomy (Correct Answer)
D. Radiotherapy
E. Bilateral mastectomy
Explanation: ***Lumpectomy***
- This patient has **non-invasive malignancy**, likely **ductal carcinoma in situ (DCIS)**, identified through microcalcifications and confirmed by excisional biopsy. For DCIS without gross invasion, the primary treatment is **surgical excision**, often a lumpectomy.
- A lumpectomy, also known as **breast-conserving surgery**, aims to remove the cancerous tissue with a margin of healthy tissue while preserving the rest of the breast.
*Tamoxifen*
- **Tamoxifen** is an **estrogen receptor modulator** used as **adjuvant therapy** for hormone-receptor-positive breast cancer, primarily after surgical removal of the tumor. It is not a primary treatment for removing the malignancy itself.
- While it might be considered after surgery depending on receptor status, it does not address the need for initial excision of the non-invasive malignancy.
*Observation with bilateral mammograms every 6 months*
- **Observation** is insufficient for confirmed non-invasive malignancy, which carries a risk of progression if untreated. **Active intervention** is required once malignancy is histologically confirmed.
- This approach might be considered for high-risk lesions or atypical hyperplasia, but not for confirmed carcinoma in situ.
*Radiotherapy*
- **Radiotherapy** is often used as **adjuvant therapy** after lumpectomy for DCIS to reduce the risk of local recurrence. It is not a standalone primary treatment for removing the initial non-invasive malignancy.
- The first step is always surgical removal of the cancerous tissue.
*Bilateral mastectomy*
- **Bilateral mastectomy** is a more aggressive surgical intervention, typically reserved for **invasive breast cancer**, widespread DCIS, or cases with very high genetic risk (e.g., BRCA mutations).
- For localized non-invasive malignancy identified through microcalcifications, a lumpectomy is generally the **most appropriate and less invasive initial surgical approach**.
Question 56: One week after undergoing sigmoidectomy with end colostomy for complicated diverticulitis, a 67-year-old man has upper abdominal pain. During the surgery, he was transfused two units of packed red blood cells. His postoperative course was uncomplicated. Two days ago, he developed fever. He is currently receiving parenteral nutrition through a central venous catheter. He has type 2 diabetes mellitus, hypertension, and hypercholesterolemia. He is oriented to person, but not to place and time. Prior to admission, his medications included metformin, valsartan, aspirin, and atorvastatin. His temperature is 38.9°C (102.0°F), pulse is 120/min, and blood pressure is 100/60 mmHg. Examination shows jaundice of the conjunctivae. Abdominal examination shows tenderness to palpation in the right upper quadrant. There is no rebound tenderness or guarding; bowel sounds are hypoactive. Laboratory studies show:
Leukocytes 13,500 /mm3
Segmented neutrophils 75 %
Serum
Aspartate aminotransferase 140 IU/L
Alanine aminotransferase 85 IU/L
Alkaline phosphatase 150 IU/L
Bilirubin
Total 2.1 mg/dL
Direct 1.3 mg/dL
Amylase 20 IU/L
Which of the following is the most likely diagnosis in this patient?
A. Acute pancreatitis
B. Small bowel obstruction
C. Hemolytic transfusion reaction
D. Anastomotic insufficiency
E. Acalculous cholecystitis (Correct Answer)
Explanation: ***Acalculous cholecystitis***
* This patient's clinical picture, including fever, **right upper quadrant tenderness**, **jaundice**, and elevated **liver enzymes** (AST, ALT, ALP, bilirubin), following a major abdominal surgery and **central venous parenteral nutrition**, is highly suggestive of acalculous cholecystitis.
* **Acalculous cholecystitis** often affects critically ill patients, especially those with trauma, burns, sepsis, or prolonged parenteral nutrition, due to gallbladder stasis and ischemia, even in the absence of gallstones.
*Acute pancreatitis*
* While the patient has upper abdominal pain, the **amylase level is normal** (20 IU/L), which rules out acute pancreatitis.
* **Acute pancreatitis** typically presents with severe epigastric pain radiating to the back and a significant elevation in amylase and lipase levels (usually 3 times the upper limit of normal).
*Small bowel obstruction*
* Symptoms of small bowel obstruction usually include **abdominal distension**, **crampy abdominal pain**, **vomiting**, and **absence of flatus/bowel movements**, along with characteristic findings on imaging.
* Although bowel sounds are hypoactive and the patient had surgery, the predominant features here (fever, jaundice, RUQ tenderness, elevated liver enzymes) point away from obstruction and more towards an inflammatory process involving the liver/biliary system.
*Hemolytic transfusion reaction*
* A **hemolytic transfusion reaction** would cause fever, chills, hemoglobinuria, flank pain, and jaundice, but would occur soon after the transfusion (within hours for acute reactions) and typically present with signs of acute kidney injury and disseminated intravascular coagulation, which are not described.
* The time frame (one week post-transfusion) and the localized right upper quadrant tenderness with liver enzyme elevations make this less likely.
*Anastomotic insufficiency*
* An **anastomotic leak** would typically present with severe abdominal pain, peritonitis (rebound tenderness, guarding), fever, and sepsis, often leading to abscess formation.
* This patient's examination **lacks rebound tenderness or guarding**, and the predominant findings of jaundice and elevated liver enzymes are not the primary features of an anastomotic leak.
Question 57: A 23-year-old woman presents to her primary care physician for knee pain. The patient states it started yesterday and has been steadily worsening. She recently joined a volleyball team to try to get into shape as she was informed that weight loss would be beneficial for her at her last physical exam. She states that she has been repetitively pivoting and twisting on her knee while playing volleyball. The patient has a past medical history of polycystic ovarian syndrome and is currently taking oral contraceptive pills. Her temperature is 98.5°F (36.9°C), blood pressure is 137/88 mmHg, pulse is 90/min, respirations are 12/min, and oxygen saturation is 98% on room air. Physical exam reveals an obese woman with facial hair. Physical exam is notable for tenderness that is elicited with palpation over the medial aspect of the tibia just inferior to the patella. Her BMI is 37 kg/m^2. The rest of the exam of the lower extremity is not remarkable. Which of the following is the most likely diagnosis?
A. Medial meniscus tear
B. Patellofemoral syndrome
C. Pes anserine bursitis (Correct Answer)
D. Osteoarthritis
E. Medial collateral ligament tear
Explanation: ***Pes anserine bursitis***
- The patient's presentation of **inferomedial knee pain**, obesity, and recent increase in activity (volleyball with pivoting/twisting motions) strongly suggests pes anserine bursitis. The pain is typically **localized to the medial aspect of the tibia**, just below the knee joint, which aligns with the physical exam findings.
- Bursitis is an **inflammatory condition** of the bursa, and the **pes anserine bursa** can become inflamed due to friction or overuse, especially in overweight individuals or those engaging in activities involving repetitive knee flexion and internal rotation.
*Medial meniscus tear*
- A medial meniscus tear typically presents with pain localized to the **medial joint line**, often accompanied by **clicking, locking, or catching sensations** in the knee, which are not described here.
- While twisting injuries can cause meniscal tears, the **specific tenderness over the medial tibia inferior to the patella** is less characteristic of a meniscal tear and more typical of pes anserine bursitis.
*Patellofemoral syndrome*
- Patellofemoral syndrome involves **anterior knee pain** that is typically worse with activities like going up or down stairs, squatting, or prolonged sitting with flexed knees.
- The pain is usually felt **around or behind the patella**, not specifically over the inferomedial aspect of the tibia.
*Osteoarthritis*
- Osteoarthritis of the knee typically presents with **gradual onset of pain**, stiffness (especially after rest), and crepitus, and is more common in older individuals or those with a history of significant joint injury.
- While obesity is a risk factor, the **acute onset of pain** and the specific focal tenderness in a 23-year-old make osteoarthritis a less likely primary diagnosis.
*Medial collateral ligament tear*
- An MCL tear results from a **valgus stress injury** to the knee, often presenting with pain and tenderness directly over the medial collateral ligament, typically spanning the joint line.
- It usually causes **instability or pain with valgus stress testing**, and while twisting can be involved, the isolated tenderness inferior to the patella is less indicative of an MCL tear without other signs of ligamentous injury.
Question 58: Five days after undergoing right knee arthroplasty for osteoarthritis, a 68-year-old man has severe pain in his right knee preventing him from participating in physical therapy. On the third postoperative day when the dressing was changed, the surgical wound appeared to be intact, slightly swollen, and had a clear secretion. He has a history of diabetes, hyperlipidemia, and hypertension. Current medications include metformin, enalapril, and simvastatin. His temperature is 37.3°C (99.1°F), pulse is 94/min, and blood pressure is 130/88 mm Hg. His right knee is swollen, erythematous, and tender to palpation. There is pain on movement of the joint. The medial parapatellar skin incision appears superficially opened in its proximal and distal part with yellow-green discharge. There is blackening of the skin on both sides of the incision. Which of the following is the next best step in the management of this patient?
A. Vacuum dressing
B. Antiseptic dressing
C. Nafcillin therapy
D. Removal of prostheses
E. Surgical debridement (Correct Answer)
Explanation: ***Surgical debridement***
- The patient presents with classic signs of **necrotizing fasciitis** or a severe wound infection: rapidly worsening pain, erythema, swelling, **yellow-green discharge**, and crucially, **blackening of the skin** (indicating tissue necrosis).
- Immediate **surgical debridement** is critical for source control, removal of necrotic tissue, and preventing further spread of infection, which can be life-threatening.
*Vacuum dressing*
- A vacuum-assisted closure (VAC) dressing is used for wound management after adequate debridement or for wounds without signs of aggressive infection to promote healing.
- Applying a VAC dressing to a wound with widespread necrosis and active infection, especially necrotizing fasciitis, without prior debridement would be ineffective and potentially harmful.
*Antiseptic dressing*
- While antiseptic dressings can help reduce bacterial load in some superficial wounds, they are entirely insufficient for deep-seated, rapidly spreading infections with tissue necrosis.
- This approach fails to address the underlying necrotic tissue and the extent of the infection, leading to rapid deterioration.
*Nafcillin therapy*
- **Antibiotic therapy** is essential for treating severe infections; however, it must be combined with source control, especially when necrosis is present.
- Giving antibiotics alone without **surgical debridement** in cases of necrotizing fasciitis is inadequate and will not prevent progression of the infection or improve patient outcomes.
*Removal of prostheses*
- While **prosthesis removal** may be necessary in some cases of established periprosthetic joint infection, it is a definitive and often late measure.
- The immediate priority in a rapidly progressing, necrotic wound infection is **surgical debridement** to remove devitalized tissue and control the local infection, prior to considering implant removal unless the infection is directly on the implant.