A 24-year-old woman with a past medical history significant only for endometriosis presents to the outpatient clinic with a 2-cm left breast mass that she first identified 6 months earlier. On review of systems, the patient states that the mass is not painful and, by her estimation, has not significantly increased in size since she first noticed it. On physical examination, there is a palpable, round, rubbery, mobile mass approximately 2 cm in diameter. Given the lesion’s characteristics and the patient’s demographics, what is the most likely diagnosis?
Q22
A 40-year-old female visits the emergency department with right upper quadrant pain and fever of 2-hours duration. She denies alcohol, cigarette, and drug use and reports no other medical problems. Body mass index is 30 kg/m^2. Her temperature is 38.5 degrees Celsius (101.3 degrees Fahrenheit), blood pressure is 130/80 mm Hg, pulse is 90/min, and respirations are 18/min. Jaundice is present in the sclera and at the base of the tongue. The abdomen is tender in the right upper quadrant. Liver function test (LFTs) reveal elevated direct and total bilirubin and alkaline phosphatase of 500 U/L. IV Ampicillin-gentamicin is administered, fluid resuscitation is initiated, and over 24 hours the patient’s fever improves. Which of the following is the next step in the management of this patient:
Q23
A 49-year-old man comes to the emergency department because of recurrent abdominal pain for 1 week. The pain is worse after eating and he has vomited twice during this period. He was hospitalized twice for acute pancreatitis during the past year; the latest being 2 months ago. There is no family history of serious illness. His only medication is a vitamin supplement. He has a history of drinking five beers a day for several years but quit 1 month ago. His temperature is 37.1°C (98.8°F), pulse is 98/min and blood pressure 110/70 mm Hg. He appears uncomfortable. Examination shows epigastric tenderness to palpation; there is no guarding or rebound. A CT scan of the abdomen shows a 6-cm low attenuation oval collection with a well-defined wall contiguous with the body of the pancreas. Which of the following is the most appropriate next step in management?
Q24
A 47-year-old woman is brought to the emergency department by her husband with the complaints of severe abdominal pain and discomfort. The pain began 2 days earlier, she describes it as radiating to her back and is associated with nausea. Her past medical history is significant for similar episodes of pain after fatty meals that resolved on its own. She drinks socially and has a 15 pack-year smoking history. Her pulse is 121/min, blood pressure is 121/71 mm Hg, and her temperature is 103.1°F (39.5°C). She has tenderness in the right upper quadrant and epigastrium with guarding and rebound tenderness. Bowel sounds are hypoactive. Part of a CBC is given below. What is the next best step in the management of this patient?
Hb%: 11 gm/dL
Total count (WBC): 13,400/mm3
Differential count:
Neutrophils: 80%
Lymphocytes: 15%
Monocytes: 5%
ESR: 45 mm/hr
C-reactive protein: 9.9 mg/dL (Normal < 3.0 mg/dL)
Q25
A 56-year-old man presents to the emergency department with severe epigastric pain that began an hour prior to presentation. He describes the pain as sharp, 10/10 in severity, and radiating to the back. Swallowing worsens the pain and causes him to cough. Before the pain started, he had been vomiting multiple times per day for the past week. The emesis was yellow and he denied ever seeing blood. Medical history is significant for poorly controlled hypertension, type II diabetes, alcohol use disorder, and 2 prior hospitalizations for acute pancreatitis. He smokes 1 pack of cigarettes per day for the last 35 years, denies illicit drug use, and drinks 3 pints of vodka per day. On physical exam, there is mediastinal crackling in synchrony with cardiac contraction on cardiac auscultation in the left lateral decubitus position. Laboratory testing is significant for leukocytosis. Which of the following is most likely the cause of this patient’s symptoms?
Q26
A 32-year-old man and his wife are sent to a fertility specialist after trying to conceive for several years without success. They have had unprotected sex several times a week. He has no history of a serious illness and does not take any medications. There are no concerns about his libido or erections. His female partner is not on contraceptive medication and has a child from a previous marriage. At the clinic, his vitals are normal. Examination of the scrotum on the right side is normal, but on the left side there are many deep and superficial ducts or vessels that feels like a bag of worms on palpation. The lesion is more apparent when the patient bears down. Semen analysis shows a low sperm count with poor motility and an increased percentage of abnormal sperms. Which of the following is the most appropriate next step in management?
Q27
A 48-year-old woman with a known past medical history significant for hypertension presents for a second opinion of a left breast lesion. The lesion was characterized as eczema by the patient's primary care physician and improved briefly after a trial of topical steroids. However, the patient is concerned that the lesion has started to grow. On physical examination, there is an erythematous, scaly lesion involving the left breast nipple-areolar complex with weeping drainage. What is the next step in the patient's management?
Q28
A 37-year-old woman is brought to the emergency department 15 minutes after falling down a flight of stairs. On arrival, she has shortness of breath, right-sided chest pain, right upper quadrant abdominal pain, and right shoulder pain. She is otherwise healthy. She takes no medications. She appears pale. Her temperature is 37°C (98.6°F), pulse is 115/min, respirations are 20/min, and blood pressure is 85/45 mm Hg. Examination shows several ecchymoses over the right chest. There is tenderness to palpation over the right chest wall and right upper quadrant of the abdomen. Bowel sounds are normal. Cardiopulmonary examination shows no abnormalities. Neck veins are flat. Which of the following is the most likely diagnosis?
Q29
A 27-year-old woman presents with acute abdominal pain in her right upper quadrant. The pain came on suddenly while she was eating dinner. After this pain she began feeling dizzy and came to the emergency department. In the ED, her blood pressure is 75/40 mmHg, pulse is 100/minute, and she is afebrile. On physical exam, she feels too light-headed to ambulate. She demonstrates normal bowel sounds with tenderness upon palpation in the right upper quadrant. The patient is deemed too unstable for imaging. An abdominal radiograph and CT are reviewed from a recent previous visit to the ED for mild abdominal pain, and are shown in Figures A and B, respectively. Which of the following specific additional findings in her history supports the most likely diagnosis?
Q30
A 38-year-old man arrives at the emergency department with severe periumbilical, colicky pain and abdominal distention for the past 2 days. He is nauseated and reports vomiting light-green emesis 8 times since yesterday morning. He has not had a bowel movement or passed any gas for the past 3 days. He has a past medical history of ventral hernia repair 5 years ago. His heart rate is 110/min, respiratory rate is 24/min, temperature is 38.0°C (100.4°F), and blood pressure is 120/90 mm Hg. The abdomen is distended and mildly tender to deep palpation. Bowel sounds are high-pitched and tinkling. Which of the following is the most likely cause?
Abdominal emergencies US Medical PG Practice Questions and MCQs
Question 21: A 24-year-old woman with a past medical history significant only for endometriosis presents to the outpatient clinic with a 2-cm left breast mass that she first identified 6 months earlier. On review of systems, the patient states that the mass is not painful and, by her estimation, has not significantly increased in size since she first noticed it. On physical examination, there is a palpable, round, rubbery, mobile mass approximately 2 cm in diameter. Given the lesion’s characteristics and the patient’s demographics, what is the most likely diagnosis?
A. Fibrocystic change
B. Invasive breast carcinoma
C. Fibroadenoma (Correct Answer)
D. Phyllodes tumor
E. Ductal carcinoma in situ
Explanation: ***Fibroadenoma***
- This diagnosis is supported by the patient's age (young woman), the **rubbery, mobile, well-circumscribed** nature of the mass, and its slow growth over 6 months without pain.
- Fibroadenomas are **benign tumors** made of both fibrous and glandular tissue, and their characteristics typically match this presentation.
*Fibrocystic change*
- While common in young women, fibrocystic changes often manifest as **multiple cysts**, generalized breast tenderness, or cyclical pain related to menstruation.
- The description of a single, non-tender, rubbery mass is less typical for fibrocystic changes.
*Invasive breast carcinoma*
- Though possible, **invasive breast cancer** in a 24-year-old woman is less common, and typically presents with a **hard, irregular, fixed mass** that may be painful or associated with skin changes.
- The description of a **rubbery, mobile** lesion not significantly increasing in size makes this less likely.
*Phyllodes tumor*
- This tumor is characterized by **rapid growth** and often reaches a large size, which is not consistent with the patient's report of slow growth over 6 months.
- While it can be benign, borderline, or malignant, its typical presentation is **faster-growing** than described.
*Ductal carcinoma in situ*
- **Ductal carcinoma in situ (DCIS)** is a non-invasive form of breast cancer that usually presents as **microcalcifications on mammography** and is often non-palpable.
- When palpable, it is typically a poorly defined lump, not a rubbery, mobile, well-circumscribed mass.
Question 22: A 40-year-old female visits the emergency department with right upper quadrant pain and fever of 2-hours duration. She denies alcohol, cigarette, and drug use and reports no other medical problems. Body mass index is 30 kg/m^2. Her temperature is 38.5 degrees Celsius (101.3 degrees Fahrenheit), blood pressure is 130/80 mm Hg, pulse is 90/min, and respirations are 18/min. Jaundice is present in the sclera and at the base of the tongue. The abdomen is tender in the right upper quadrant. Liver function test (LFTs) reveal elevated direct and total bilirubin and alkaline phosphatase of 500 U/L. IV Ampicillin-gentamicin is administered, fluid resuscitation is initiated, and over 24 hours the patient’s fever improves. Which of the following is the next step in the management of this patient:
A. Extracorporeal shock wave lithotripsy
B. Urgent open cholecystectomy
C. Endoscopic retrograde cholangiopancreatography (ERCP) (Correct Answer)
D. Elective laparoscopic cholecystectomy
E. Administer bile acids
Explanation: ***Endoscopic retrograde cholangiopancreatography (ERCP)***
- The patient presents with classic signs of **acute cholangitis** (Charcot's triad: fever, right upper quadrant pain, and jaundice), elevated direct bilirubin, and alkaline phosphatase. **Urgent biliary decompression** via ERCP is the standard next step to relieve obstruction caused by gallstones and prevent progression to septic shock.
- Although the patient's fever improved with antibiotics, it does not mean the obstruction has resolved. Biliary drainage is crucial, especially given the rapid onset and systemic inflammatory response.
*Extracorporeal shock wave lithotripsy*
- **ESWL** is primarily used for **kidney stones** or occasionally for large, solitary **gallbladder stones** that do not cause acute obstruction.
- It is **ineffective** for common bile duct stones causing acute cholangitis, where immediate drainage is required.
*Urgent open cholecystectomy*
- **Open cholecystectomy** is the removal of the gallbladder. While the gallbladder may be the source of the stones, this procedure **does not directly address the common bile duct obstruction** causing cholangitis.
- Furthermore, cholecystectomy is generally contraindicated during acute cholangitis due to the increased risk of complications, and the priority is to relieve the obstruction first.
*Elective laparoscopic cholecystectomy*
- **Cholecystectomy** is indicated for symptomatic gallstones, but it is typically performed **electively** after acute inflammation and obstruction have been resolved.
- This patient requires urgent intervention for common bile duct obstruction, making an elective procedure inappropriate at this stage.
*Administer bile acids*
- **Oral bile acids** (e.g., ursodeoxycholic acid) can be used to **dissolve small cholesterol gallstones** in the gallbladder.
- They are **ineffective** and contraindicated for the rapid resolution of acute biliary obstruction caused by common bile duct stones and cholangitis.
Question 23: A 49-year-old man comes to the emergency department because of recurrent abdominal pain for 1 week. The pain is worse after eating and he has vomited twice during this period. He was hospitalized twice for acute pancreatitis during the past year; the latest being 2 months ago. There is no family history of serious illness. His only medication is a vitamin supplement. He has a history of drinking five beers a day for several years but quit 1 month ago. His temperature is 37.1°C (98.8°F), pulse is 98/min and blood pressure 110/70 mm Hg. He appears uncomfortable. Examination shows epigastric tenderness to palpation; there is no guarding or rebound. A CT scan of the abdomen shows a 6-cm low attenuation oval collection with a well-defined wall contiguous with the body of the pancreas. Which of the following is the most appropriate next step in management?
A. Magnetic resonance cholangiopancreatography
B. CT-guided percutaneous drainage (Correct Answer)
C. Middle segment pancreatectomy
D. Laparoscopic surgical drainage
E. Distal pancreatectomy
Explanation: ***CT-guided percutaneous drainage***
- The patient presents with a **symptomatic pancreatic pseudocyst** (recurrent abdominal pain, vomiting, epigastric tenderness) that is 6 cm and has a well-defined wall.
- Given the patient's symptoms and the size/maturity of the pseudocyst, **CT-guided percutaneous drainage** is the most appropriate initial management to relieve symptoms and drain the fluid.
*Magnetic resonance cholangiopancreatography*
- **MRCP** is primarily used to visualize the **biliary and pancreatic ductal systems**, often to identify stones, strictures, or anatomical variations.
- While it can provide more detailed imaging of the pancreatic ducts, it is not a treatment for a symptomatic pseudocyst and would not relieve the patient's immediate pain and vomiting.
*Middle segment pancreatectomy*
- **Pancreatectomies** are **surgical resections** of part or all of the pancreas, typically reserved for tumors, severe necrosis, or intractable pain from chronic pancreatitis not amenable to less invasive treatments.
- This is an **overly aggressive surgical intervention** for a pseudocyst that can likely be managed with drainage.
*Laparoscopic surgical drainage*
- **Laparoscopic internal drainage** (e.g., cystogastrostomy) is an option for mature, symptomatic pseudocysts, but it is typically performed after a period of observation and if percutaneous drainage is unsuccessful or not feasible.
- Percutaneous drainage is generally preferred as the **initial less invasive approach** for managing symptomatic pseudocysts.
*Distal pancreatectomy*
- **Distal pancreatectomy** involves the surgical removal of the body and tail of the pancreas and is indicated for conditions such as tumors localized in these regions or for specific cases of chronic pancreatitis.
- It is an **aggressive surgical procedure** and not the first-line treatment for a symptomatic pancreatic pseudocyst, especially if less invasive options are available.
Question 24: A 47-year-old woman is brought to the emergency department by her husband with the complaints of severe abdominal pain and discomfort. The pain began 2 days earlier, she describes it as radiating to her back and is associated with nausea. Her past medical history is significant for similar episodes of pain after fatty meals that resolved on its own. She drinks socially and has a 15 pack-year smoking history. Her pulse is 121/min, blood pressure is 121/71 mm Hg, and her temperature is 103.1°F (39.5°C). She has tenderness in the right upper quadrant and epigastrium with guarding and rebound tenderness. Bowel sounds are hypoactive. Part of a CBC is given below. What is the next best step in the management of this patient?
Hb%: 11 gm/dL
Total count (WBC): 13,400/mm3
Differential count:
Neutrophils: 80%
Lymphocytes: 15%
Monocytes: 5%
ESR: 45 mm/hr
C-reactive protein: 9.9 mg/dL (Normal < 3.0 mg/dL)
A. Serum lipase levels
B. Ultrasound of the gallbladder (Correct Answer)
C. Erect abdominal X-ray
D. Upper GI endoscopy
E. Ultrasound of the appendix
Explanation: ***Ultrasound of the gallbladder***
- The patient presents with classic symptoms of **acute cholecystitis**, including severe right upper quadrant pain radiating to the back, fever, leukocytosis, and a history of similar pain after fatty meals.
- An ultrasound of the gallbladder is the **gold standard** for diagnosing cholecystitis, as it can visualize gallstones, gallbladder wall thickening, pericholecystic fluid, and sonographic Murphy's sign.
*Serum lipase levels*
- While pancreatic involvement can occur, **serum lipase** is primarily used to diagnose **pancreatitis**, which typically presents with more severe epigastric pain and may or may not involve gallstones.
- The clinical picture here is more suggestive of cholecystitis, where gallbladder imaging is the priority.
*Erect abdominal X-ray*
- An **erect abdominal X-ray** is useful for detecting **free air under the diaphragm** in cases of bowel perforation or to assess for bowel obstruction.
- It is not the primary diagnostic tool for cholecystitis, as gallstones are often radiolucent and it does not provide detailed information about the gallbladder wall or surrounding structures.
*Upper GI endoscopy*
- **Upper GI endoscopy** is indicated for evaluating **esophageal, gastric, or duodenal pathologies**, such as ulcers, gastritis, or tumors.
- While peptic ulcer disease can cause epigastric pain, the patient's symptoms, especially the radiation to the back, fever, and history of pain after fatty meals, are more consistent with gallbladder disease, making endoscopy a less immediate diagnostic step.
*Ultrasound of the appendix*
- An **ultrasound of the appendix** is primarily used to diagnose **appendicitis**, which typically presents with periumbilical pain migrating to the right lower quadrant.
- The patient's pain is localized to the right upper quadrant and epigastrium, making appendicitis highly unlikely.
Question 25: A 56-year-old man presents to the emergency department with severe epigastric pain that began an hour prior to presentation. He describes the pain as sharp, 10/10 in severity, and radiating to the back. Swallowing worsens the pain and causes him to cough. Before the pain started, he had been vomiting multiple times per day for the past week. The emesis was yellow and he denied ever seeing blood. Medical history is significant for poorly controlled hypertension, type II diabetes, alcohol use disorder, and 2 prior hospitalizations for acute pancreatitis. He smokes 1 pack of cigarettes per day for the last 35 years, denies illicit drug use, and drinks 3 pints of vodka per day. On physical exam, there is mediastinal crackling in synchrony with cardiac contraction on cardiac auscultation in the left lateral decubitus position. Laboratory testing is significant for leukocytosis. Which of the following is most likely the cause of this patient’s symptoms?
A. Ulcerative changes in the gastric mucosa
B. Inflammation of the pancreas
C. Transmural esophageal rupture (Correct Answer)
D. Coronary artery occlusion
E. Dissection of the aorta
Explanation: ***Transmural esophageal rupture***
- The combination of **severe epigastric pain radiating to the back**, worsening with swallowing and causing coughing, a history of **repeated vomiting**, and the finding of **mediastinal crackling (Hamman's sign)** strongly points to a spontaneous esophageal rupture, also known as **Boerhaave syndrome**.
- The patient's history of **alcohol use disorder** and **recurrent pancreatitis** can lead to altered esophageal motility and increased intragastric pressure, predisposing him to such a rupture following protracted vomiting.
*Ulcerative changes in the gastric mucosa*
- While **gastric ulcers** can cause epigastric pain, they typically do not present with acute, 10/10 severity pain radiating to the back and causing mediastinal crackling.
- Vomiting associated with ulcers might contain blood (**hematemesis**), which was explicitly denied by the patient.
*Inflammation of the pancreas*
- This patient has a history of **acute pancreatitis** and risk factors (alcohol abuse). However, the highly acute onset of severe pain, especially with mediastinal crackling and pain worsening after swallowing, is not typical for **isolated pancreatitis**.
- While pancreatitis can cause severe epigastric pain radiating to the back, the specific finding of **Hamman's sign** makes esophageal rupture a more likely diagnosis.
*Coronary artery occlusion*
- **Myocardial infarction** can cause severe chest or epigastric pain, sometimes radiating to the back or left arm, but is generally associated with symptoms like dyspnea, diaphoresis, and ECG changes.
- It would not typically present with **recurrent vomiting** for a week prior to presentation or **mediastinal crackling**.
*Dissection of the aorta*
- **Aortic dissection** can cause sudden, severe radiating pain, often described as "tearing wet cement." However, its acute presentation usually involves pain radiating to the back or neck, and it is rarely associated with repeated prior vomiting or mediastinal crackling (unless the dissection causes rupture into the mediastinum, which is a late and highly lethal complication).
- The type of pain (worsening with swallowing, causing coughing) and the presence of **Hamman's sign** are more pathognomonic for esophageal perforation.
Question 26: A 32-year-old man and his wife are sent to a fertility specialist after trying to conceive for several years without success. They have had unprotected sex several times a week. He has no history of a serious illness and does not take any medications. There are no concerns about his libido or erections. His female partner is not on contraceptive medication and has a child from a previous marriage. At the clinic, his vitals are normal. Examination of the scrotum on the right side is normal, but on the left side there are many deep and superficial ducts or vessels that feels like a bag of worms on palpation. The lesion is more apparent when the patient bears down. Semen analysis shows a low sperm count with poor motility and an increased percentage of abnormal sperms. Which of the following is the most appropriate next step in management?
A. Pulsatile GNRH
B. Ligation of processus vaginalis
C. Microsurgical varicocelectomy (Correct Answer)
D. No therapy at this time
E. Intracytoplasmic sperm injection
Explanation: ***Microsurgical varicocelectomy***
- The clinical presentation of a "bag of worms" on scrotal palpation that becomes more apparent with bearing down is classic for a **varicocele**.
- A varicocele is a common cause of **male infertility** due to impaired spermatogenesis, often leading to low sperm count, poor motility, and abnormal sperm morphology, which are all present in this patient's semen analysis. **Microsurgical varicocelectomy** is the most appropriate next step to improve semen parameters and increase the chances of natural conception.
*Pulsatile GNRH*
- **Pulsatile GnRH** is used to treat **hypogonadotropic hypogonadism**, a condition characterized by low testosterone and low FSH/LH, which is not suggested by the clinical picture or symptoms here.
- This patient's libido and erections are normal, indicating adequate testosterone levels, making pulsatile GnRH an unlikely treatment.
*Ligation of processus vaginalis*
- **Ligation of the processus vaginalis** is a surgical procedure primarily used to treat a **patent processus vaginalis**, which can cause a **communicating hydrocele** or an **indirect inguinal hernia**.
- This procedure is not indicated for the management of varicocele or male infertility directly related to sperm production issues.
*No therapy at this time*
- The patient has been trying to conceive for several years, has a clear diagnosis of varicocele, and significant abnormalities in his **semen analysis**, indicating a need for intervention.
- Delaying therapy would mean a continued inability to conceive naturally, which is the primary concern for the couple.
*Intracytoplasmic sperm injection*
- **Intracytoplasmic sperm injection (ICSI)** is an assisted reproductive technology used in cases of severe male factor infertility or failed IVF rather than a primary treatment for a correctable cause like varicocele.
- It is typically considered when simpler, less invasive, or corrective treatments have failed or are not applicable. Optimizing natural conception through varicocele repair is usually the first-line approach in such cases.
Question 27: A 48-year-old woman with a known past medical history significant for hypertension presents for a second opinion of a left breast lesion. The lesion was characterized as eczema by the patient's primary care physician and improved briefly after a trial of topical steroids. However, the patient is concerned that the lesion has started to grow. On physical examination, there is an erythematous, scaly lesion involving the left breast nipple-areolar complex with weeping drainage. What is the next step in the patient's management?
A. Oral corticosteroids
B. Left breast MRI
C. Punch biopsy of the nipple, followed by bilateral mammography (Correct Answer)
D. Maintain regular annual mammography appointment
E. Bilateral breast ultrasound
Explanation: ***Punch biopsy of the nipple, followed by bilateral mammography***
- The presentation of an **erythematous, scaly lesion** involving the **nipple-areolar complex** with weeping drainage, especially after failing topical steroids, is highly suggestive of **Paget's disease of the breast**.
- A **punch biopsy** is essential for definitive diagnosis, and if confirmed, **bilateral mammography** is crucial to assess for underlying ductal carcinoma in situ or invasive breast cancer, which is present in >90% of Paget's cases.
*Oral corticosteroids*
- While topical steroids initially improved the lesion, the failure of sustained improvement and the **progression of symptoms** suggest a more serious underlying pathology than simple eczema.
- Using systemic corticosteroids could **mask the progression** of a malignancy without addressing the root cause, delaying definitive diagnosis and treatment.
*Left breast MRI*
- **MRI** is a sensitive imaging modality for breast tissue but is typically used for **staging** a known malignancy or for high-risk screening, not as the primary diagnostic tool for a nipple lesion.
- A **biopsy** is required first to establish the diagnosis of Paget's disease or other malignancy before considering MRI for the extent of disease.
*Maintain regular annual mammography appointment*
- This approach is insufficient given the patient's **new and concerning symptoms** that are highly suspicious for **Paget's disease**, which often presents with abnormal mammographic findings or can be occult on mammography entirely.
- A regular screening schedule would significantly **delay diagnosis and treatment** of a potentially aggressive breast cancer.
*Bilateral breast ultrasound*
- **Ultrasound** can detect solid masses or cysts and is often used as an adjunct to mammography, especially in dense breasts, or to evaluate palpable findings.
- However, for a **nipple-areolar lesion** suspicious for Paget's disease, a **biopsy** is the most direct and definitive diagnostic step, as ultrasound may not adequately visualize the primary lesion or differentiate it from benign conditions.
Question 28: A 37-year-old woman is brought to the emergency department 15 minutes after falling down a flight of stairs. On arrival, she has shortness of breath, right-sided chest pain, right upper quadrant abdominal pain, and right shoulder pain. She is otherwise healthy. She takes no medications. She appears pale. Her temperature is 37°C (98.6°F), pulse is 115/min, respirations are 20/min, and blood pressure is 85/45 mm Hg. Examination shows several ecchymoses over the right chest. There is tenderness to palpation over the right chest wall and right upper quadrant of the abdomen. Bowel sounds are normal. Cardiopulmonary examination shows no abnormalities. Neck veins are flat. Which of the following is the most likely diagnosis?
A. Splenic laceration
B. Liver hematoma (Correct Answer)
C. Pneumothorax
D. Duodenal hematoma
E. Small bowel perforation
Explanation: ***Liver hematoma***
- The patient's presentation with **right upper quadrant abdominal pain**, **right shoulder pain** (referred pain from diaphragmatic irritation), and **hypotension** following a fall points strongly to **liver injury**.
- The liver is the **most commonly injured organ** in blunt abdominal trauma due to its size and position.
*Splenic laceration*
- While splenic laceration can cause hypovolemic shock, pain is typically localized to the **left upper quadrant** and left shoulder (**Kehr's sign**), not the right.
- The ecchymoses and tenderness are predominantly on the **right side** of the chest and abdomen.
*Pneumothorax*
- A pneumothorax would typically present with **unilateral diminished breath sounds**, **hyperresonance to percussion**, and potentially **tracheal deviation**, none of which are mentioned.
- The patient's **blood pressure is low**, which is more suggestive of significant hemorrhage than an isolated pneumothorax, especially with **flat neck veins**.
*Duodenal hematoma*
- A duodenal hematoma typically presents with **epigastric pain**, **vomiting**, and symptoms of **gastric outlet obstruction**, often days after the injury.
- It does not typically cause **referred shoulder pain** or immediate **hypovolemic shock** as seen here.
*Small bowel perforation*
- Small bowel perforation would present with signs of **peritonitis**, such as **rebound tenderness**, **guarding**, and absent or diminished bowel sounds due to inflammation from bowel contents.
- While there is abdominal pain, the **bowel sounds are normal**, and the primary symptoms align more with **hemorrhage**.
Question 29: A 27-year-old woman presents with acute abdominal pain in her right upper quadrant. The pain came on suddenly while she was eating dinner. After this pain she began feeling dizzy and came to the emergency department. In the ED, her blood pressure is 75/40 mmHg, pulse is 100/minute, and she is afebrile. On physical exam, she feels too light-headed to ambulate. She demonstrates normal bowel sounds with tenderness upon palpation in the right upper quadrant. The patient is deemed too unstable for imaging. An abdominal radiograph and CT are reviewed from a recent previous visit to the ED for mild abdominal pain, and are shown in Figures A and B, respectively. Which of the following specific additional findings in her history supports the most likely diagnosis?
A. Symptoms that began after a fatty meal
B. Use of oral contraceptives (OCPs) for birth control (Correct Answer)
C. A 15 pack/year history of smoking
D. A history of Epstein-Barr virus and participation in rugby
E. An extensive history of sexually transmitted diseases (STDs) and pelvic inflammatory disease (PID)
Explanation: ***Use of oral contraceptives (OCPs) for birth control***
- The patient's presentation with acute right upper quadrant pain, **hemodynamic instability** (BP 75/40 mmHg, pulse 100/minute, dizziness), and previous imaging showing a hepatic lesion (implied by the question context though images aren't provided) strongly suggests a ruptured **hepatic adenoma**.
- **Oral contraceptive pill (OCP) use** is a well-established risk factor for the development and rupture of hepatic adenomas due to their estrogen content, which promotes growth.
*Symptoms that began after a fatty meal*
- Acute right upper quadrant pain exacerbated by a **fatty meal** is classic for **cholecystitis** or **biliary colic**.
- However, the patient's **hemodynamic instability** is not typical for uncomplicated cholecystitis, and hepatic adenoma rupture is a more fitting explanation for the sudden onset of profound shock.
*A 15 pack/year history of smoking*
- Smoking is a risk factor for various abdominal conditions, including **peptic ulcer disease** and certain **malignancies**.
- It is not a direct risk factor for **hepatic adenoma rupture** and does not explain the acute, life-threatening presentation in this young woman as well as OCP use.
*A history of Epstein-Barr virus and participation in rugby*
- A history of Epstein-Barr virus (EBV) and contact sports like rugby is associated with an increased risk of **splenic rupture**, especially if splenomegaly is present.
- While splenic rupture can cause acute abdominal pain and hypovolemic shock, the pain would typically be in the **left upper quadrant**, not the right.
*An extensive history of sexually transmitted diseases (STDs) and pelvic inflammatory disease (PID)*
- STDs and PID are risk factors for **ectopic pregnancy** (which can cause acute abdominal pain and rupture, leading to shock) and **Fitz-Hugh-Curtis syndrome** (perihepatitis causing RUQ pain).
- However, the patient's age and sex would make these considerations relevant, but the specific localization of pain to the right upper quadrant and the strong association with OCPs point more directly to a hepatic pathology.
Question 30: A 38-year-old man arrives at the emergency department with severe periumbilical, colicky pain and abdominal distention for the past 2 days. He is nauseated and reports vomiting light-green emesis 8 times since yesterday morning. He has not had a bowel movement or passed any gas for the past 3 days. He has a past medical history of ventral hernia repair 5 years ago. His heart rate is 110/min, respiratory rate is 24/min, temperature is 38.0°C (100.4°F), and blood pressure is 120/90 mm Hg. The abdomen is distended and mildly tender to deep palpation. Bowel sounds are high-pitched and tinkling. Which of the following is the most likely cause?
A. Viral gastroenteritis
B. Cholecystitis
C. Small bowel obstruction (Correct Answer)
D. Diverticulitis
E. Crohn's disease
Explanation: ***Small bowel obstruction***
- The patient's presentation with **colicky periumbilical pain**, **abdominal distention**, **vomiting of light-green emesis**, and **absence of bowel movements or gas passage** strongly suggests a small bowel obstruction.
- The history of **ventral hernia repair 5 years ago** raises suspicion for **adhesions** as a common cause of small bowel obstruction.
*Viral gastroenteritis*
- This condition typically presents with **diarrhea** and vomiting, but usually **without significant abdominal distention** or absent flatus, which are prominent in this case.
- Unlike small bowel obstruction, gastroenteritis does not cause **tinkling bowel sounds** or significant obstruction to the passage of stool and gas.
*Cholecystitis*
- Cholecystitis usually presents with **right upper quadrant pain**, often radiating to the back or shoulder, and can be associated with **fever and nausea/vomiting**.
- However, it does not typically cause **diffuse abdominal distention**, absent bowel movements/flatus, or **high-pitched, tinkling bowel sounds**.
*Diverticulitis*
- Diverticulitis frequently presents with **left lower quadrant pain**, fever, and changes in bowel habits, though constipation can occur.
- It is less likely to cause the **severe, colicky periumbilical pain**, marked abdominal distention, and signs of complete obstruction seen here.
*Crohn's disease*
- Crohn's disease can cause abdominal pain, diarrhea, and weight loss, and in severe cases, can lead to **strictures and obstruction**.
- However, an acute presentation with **severe, colicky periumbilical pain**, vomiting of light-green emesis, and complete obstruction without a prior diagnosis or known flares makes a primary small bowel obstruction due to adhesions more likely in this context.