A 58-year-old man with a history of chronic obstructive pulmonary disease is evaluated in the pulmonary function laboratory. The FEV1 is 1.1 L, the FVC is 2.9 L, and the TLC is 7.8 L (predicted 6.0 L). After administration of an inhaled bronchodilator, FEV1 increases to 1.3 L and FVC increases to 3.1 L. Which of the following best characterizes the physiological basis of his increased TLC?

Respiratory mechanics and work of breathing
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Pulmonary volumes and capacities
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Spirometry interpretation
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Flow-volume loops
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Airway resistance determinants
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Control of breathing
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Central and peripheral chemoreceptors
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Respiratory centers in the brainstem
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Dyspnea mechanisms
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Integrated respiratory responses
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