General Surgery Principles Practice Questions

Q: Catgut suture is derived from which part of the sheep?

Intestine. **Explanation:** **Correct Answer: B. Intestine** Catgut is a natural, absorbable, monofilament suture. Despite its name, it is not derived from cats. It is manufactured from the **submucosa of the small intestine of sheep** or the **serosa of the bovine (cattle) intestine**. The high collagen content in these layers provides the necessary tensile strength required for surgical closure. **Analysis of Incorrect Options:** * **A. Stomach:** While the stomach contains collagen, it is not used for suture production due to the lack of uniform tensile strength and the difficulty in processing the thick muscular layers compared to the small intestine. * **C. Muscle:** Muscle tissue is primarily composed of contractile proteins (actin and myosin) rather than the structural collagen fibers required to create a durable suture. * **D. Ligaments:** Although ligaments are rich in collagen, they are too dense and inelastic to be processed into the fine, flexible strands needed for surgical suturing. **Clinical Pearls for NEET-PG:** * **Absorption:** Catgut is absorbed by **proteolysis** (enzymatic degradation) by polymorphonuclear leukocytes, unlike synthetic absorbable sutures (like Vicryl), which are absorbed by **hydrolysis**. * **Types:** * *Plain Catgut:* Loses tensile strength in 7–10 days; fully absorbed in 60–70 days. * *Chromic Catgut:* Treated with chromium salts to delay absorption and reduce tissue reaction. Loses strength in 14–21 days; absorbed in 90 days. * **Usage:** It is rarely used today in clean surgeries due to high tissue reactivity but remains a classic exam topic. It is contraindicated in infected tissues as it degrades rapidly.

Q: Which of the following is the most commonly used site for Deep Brain Stimulation to reduce the frequency of Parkinsonism symptoms?

Subthalamic Nucleus. ### Explanation **Deep Brain Stimulation (DBS)** is a neurosurgical procedure involving the implantation of electrodes into specific brain targets to modulate abnormal electrical signals. In the management of Parkinson’s Disease (PD), DBS is indicated for patients with motor fluctuations or tremors that are refractory to medical therapy. **Why Subthalamic Nucleus (STN) is the Correct Answer:** The **Subthalamic Nucleus (STN)** is the most common and preferred target for DBS in Parkinson’s Disease. Stimulating the STN effectively reduces the "off" time and allows for a significant reduction in the dosage of dopaminergic medications (like Levodopa). It is particularly effective for treating bradykinesia, rigidity, and tremors. **Analysis of Incorrect Options:** * **Globus Pallidus (GPi):** The Globus Pallidus Internus is the second most common site. While it is excellent for reducing medication-induced dyskinesias, it does not typically allow for the same degree of medication reduction as STN-DBS. * **Striatus & Putamen:** These structures are part of the basal ganglia circuitry involved in the pathology of PD. However, they are not used as primary targets for DBS because stimulating them does not provide the same therapeutic modulation of the motor circuit as the STN or GPi. **NEET-PG High-Yield Pearls:** * **Target for Essential Tremor:** The **Ventral Intermediate Nucleus (Vim)** of the Thalamus is the preferred DBS target for Essential Tremor and Parkinsonian tremor (though it doesn't help with bradykinesia). * **Target for Dystonia:** The **Globus Pallidus Internus (GPi)** is the primary target. * **Contraindication:** DBS is generally avoided in patients with significant cognitive impairment or untreated depression, as STN-DBS can sometimes worsen neuropsychiatric symptoms. * **Mechanism:** DBS acts like a "functional lesion," inhibiting overactive nuclei in the indirect pathway of the basal ganglia.

Q: A 20-year-old male patient presented to the ER with complaints of abdominal pain, nausea, and vomiting. The pain was initially peri-umbilical in nature; however, with time, the pain worsened and shifted to the right lower quadrant. On palpating the abdomen, tenderness is present over the right lower quadrant with guarding. The patient is febrile and lab reports show leukocytosis. An emergency laparotomy is planned, and the inflamed organ is identified by the confluence of taenia coli. Which position of the above-mentioned organ is considered to be the most dangerous position?

B. ***Position B (Retrocecal)*** - The **retrocecal position** is most dangerous because the appendix lies behind the **cecum**, masking classic signs of appendicitis and leading to **delayed diagnosis**. - This position increases the risk of **perforation** and **abscess formation** due to late presentation, as typical **McBurney's point tenderness** may be absent. *Position A (Pelvic/Descending)* - In this position, the appendix descends into the **pelvis**, causing **suprapubic pain** and **urinary symptoms** rather than classic right lower quadrant pain. - While symptoms may be atypical, the appendix is more accessible and **less likely to perforate** compared to retrocecal position. *Position C (Subcecal)* - The appendix lies below the **cecum**, typically causing **right lower quadrant pain** with more obvious clinical signs. - This position allows for **easier clinical diagnosis** and has a **lower risk of complications** due to better accessibility. *Position D (Paracecal/Lateral)* - The appendix extends laterally alongside the **cecum**, producing **classic McBurney's point tenderness**. - This position has **predictable symptoms** and is **easily identified clinically**, making it less dangerous than retrocecal positioning.

Q: A 80-year-old male presented with a lung abscess in the left upper zone. What is the best treatment modality?

Antibiotics according to identified organisms. **Explanation:** The primary management of a lung abscess is **medical therapy**. Unlike abscesses in other parts of the body that require immediate surgical drainage, lung abscesses usually communicate with the bronchial tree, allowing for natural drainage through expectoration. **1. Why Option A is Correct:** Systemic **antibiotics** are the cornerstone of treatment. Since lung abscesses are often polymicrobial (involving anaerobes and aerobes), empirical therapy is started and then tailored based on culture and sensitivity from sputum or bronchoalveolar lavage. Treatment is prolonged, often lasting 4–6 weeks, until the cavity disappears or only a small stable scar remains on imaging. **2. Why Incorrect Options are Wrong:** * **Surgical Drainage (Option B):** Surgery (lobectomy or pneumonectomy) is reserved for complications like massive hemoptysis, suspicion of malignancy, or failure of medical therapy (refractory cases). It is never the first-line treatment. * **Tube Thoracostomy (Option C):** This is the treatment for **empyema** (pus in the pleural space). Inserting a chest tube into a lung abscess is generally avoided as it can lead to a bronchopleural fistula. Percutaneous drainage is only considered if the patient is septic and not responding to antibiotics. * **Observation (Option D):** A lung abscess is a serious infection that can lead to sepsis or rupture; "wait and watch" is inappropriate. **Clinical Pearls for NEET-PG:** * **Most common cause:** Aspiration (often due to poor oral hygiene or altered consciousness). * **Most common site:** Posterior segment of the right upper lobe or superior segment of the right lower lobe (due to the anatomy of the right main bronchus). * **Indications for Surgery:** Large cavity (>6 cm), refractory to antibiotics, or life-threatening hemoptysis. * **Key sign on X-ray:** An air-fluid level within a thick-walled cavity.

Q: All of the following are true regarding sebaceous cysts EXCEPT:

It only occurs on the face and scalp.. **Explanation:** The correct answer is **B** because sebaceous cysts can occur on any hair-bearing area of the body where sebaceous glands are present. While the face, scalp, and neck are the most common sites, they are frequently found on the trunk, scrotum, and labia. They are notably absent only on the palms and soles, which lack hair follicles. **Analysis of Options:** * **Option A:** Sebaceous cysts are a type of **epidermoid cyst**. They result from the obstruction of a sebaceous duct, leading to the accumulation of sebum and desquamated epithelium within a sac lined by squamous epithelium. * **Option C:** If the sebum escapes through the punctum and hardens (desiccates) on the surface, it can form a slow-growing, keratinized projection known as a **sebaceous horn**. * **Option D:** The **punctum** is a pathognomonic feature. It is a small, black opening on the skin surface representing the blocked duct orifice. It is often tethered to the underlying cyst. **High-Yield Clinical Pearls for NEET-PG:** * **Cock’s Peculiar Tumor:** This occurs when a sebaceous cyst on the scalp ulcerates and becomes infected, resembling a Squamous Cell Carcinoma (Fungating growth). * **Gardner’s Syndrome:** Multiple sebaceous (epidermoid) cysts are a known extra-intestinal manifestation of this syndrome. * **Treatment:** The gold standard is **complete surgical excision** including the cyst wall to prevent recurrence. If infected, incision and drainage (I&D) are performed first. * **Content:** The cyst contains "cheesy" material (sebum) which has a characteristic offensive odor.

Q: Which of the following is NOT a differential diagnosis for acute scrotum?

Testicular cancer. **Explanation:** The term **"Acute Scrotum"** refers to a clinical emergency characterized by the sudden onset of pain, swelling, and/or redness of the scrotum. The differential diagnosis for acute scrotum focuses on conditions that present **acutely** (within hours to a few days). **Why Testicular Cancer is the correct answer:** Testicular cancer typically presents as a **painless, hard, slow-growing mass** that is inseparable from the testis. While 10% of cases may present with acute pain due to intratumoral hemorrhage, it is fundamentally a chronic/subacute condition and is not considered a primary differential for the "acute scrotum" syndrome. **Analysis of Incorrect Options:** * **Testicular Torsion:** The most critical surgical emergency. It presents with sudden, severe pain, a high-riding testis, and a negative Prehn’s sign. * **Epididymitis/Epididymo-orchitis:** The most common cause of acute scrotum in post-pubertal males. It usually presents with fever, dysuria, and a positive Prehn’s sign (relief of pain on elevation of the scrotum). * **Hydatid Torsion (Torsion of the Appendix Testis):** The most common cause of acute scrotum in children (ages 7-12). It is characterized by the pathognomonic **"Blue Dot Sign"** on the upper pole of the testis. **NEET-PG High-Yield Pearls:** * **Golden Period:** For testicular torsion, detorsion within **6 hours** has a >90% salvage rate; this drops to <10% after 24 hours. * **Investigation of Choice:** Color Doppler Ultrasound is the gold standard to differentiate torsion (absent blood flow) from epididymitis (increased blood flow). * **Management:** If torsion is suspected clinically, immediate **surgical exploration** should not be delayed for imaging.

Q: Graft survival for the first 48 hours is primarily due to which of the following?

Absorption of nutrients into the graft. **Explanation:** The survival of a skin graft occurs in three distinct chronological stages: **Plasmatic Imbibition, Inosculation, and Revascularization.** 1. **Plasmatic Imbibition (First 24–48 hours):** Immediately after transplantation, the graft is avascular. It survives by passively absorbing nutrients and oxygen from the underlying host capillary bed via diffusion. This process causes the graft to increase in weight by approximately 40%. This is the primary mechanism for survival during the first 48 hours. 2. **Inosculation (48–72 hours):** This is the "alignment" phase where donor and recipient capillaries establish a physical connection (the "kissing" of vessels). 3. **Revascularization/Angiogenesis (Day 4–7):** New blood vessels grow from the recipient bed into the graft, establishing definitive circulation. **Analysis of Incorrect Options:** * **Option B & C:** Alignment of capillaries (Inosculation) and full vascularization occur only after the initial 48-hour window. The graft would necrose if it relied on these processes for immediate survival. * **Option D:** Lymphatic circulation is the last to be restored, typically beginning around day 5–7 and completing by the second week. **NEET-PG High-Yield Pearls:** * **Primary mechanism of graft failure:** Hematoma (prevents contact between graft and bed, blocking imbibition). * **Most common cause of graft failure:** Infection (specifically *Streptococcus pyogenes*). * **Full-thickness grafts (FTSG):** Rely more heavily on rapid inosculation compared to split-thickness grafts (STSG) because they are thicker and imbibition is less efficient. * **The "Take":** A graft is considered "taken" once revascularization is complete.

Question 1

Catgut suture is derived from which part of the sheep?

Accepted Answer

Intestine

Answer

Stomach

Answer

Muscle

Answer

Ligaments

Question 2

Which of the following is the most commonly used site for Deep Brain Stimulation to reduce the frequency of Parkinsonism symptoms?

Accepted Answer

Subthalamic Nucleus

Answer

Striatus

Answer

Globus Pallidus

Answer

Putamen

Question 3

A 20-year-old male patient presented to the ER with complaints of abdominal pain, nausea, and vomiting. The pain was initially peri-umbilical in nature; however, with time, the pain worsened and shifted to the right lower quadrant. On palpating the abdomen, tenderness is present over the right lower quadrant with guarding. The patient is febrile and lab reports show leukocytosis. An emergency laparotomy is planned, and the inflamed organ is identified by the confluence of taenia coli. Which position of the above-mentioned organ is considered to be the most dangerous position?

Accepted Answer

B

Answer

D

Answer

A

Answer

C

Question 4

A 80-year-old male presented with a lung abscess in the left upper zone. What is the best treatment modality?

Accepted Answer

Antibiotics according to identified organisms

Answer

Surgical drainage

Answer

Tube thoracostomy

Answer

Observation (wait and watch)

Question 5

Spigelian hernia occurs through which anatomical structure?

Accepted Answer

Aponeurotic layer between the rectus muscle and the semilunar line

Answer

Superior lumbar triangle

Answer

Membrane covering the canal between the pubic bone and ischium

Answer

Inferior lumbar triangle

Question 6

Post-splenectomy, which of the following infections is not common?

Accepted Answer

Disseminated herpes zoster

Answer

Pneumococcus

Answer

H. influenzae

Answer

Salmonella

Question 7

All of the following are true regarding sebaceous cysts EXCEPT:

Accepted Answer

It only occurs on the face and scalp.

Answer

It is classified as an epidermoid cyst.

Answer

If ulcerated, it can become a sebaceous horn.

Answer

It characteristically displays a punctum.

Question 8

What is the treatment for bilateral soft tissue undercut?

Accepted Answer

Removal of the tissue on one side only

Answer

Removal of tissue on both sides

Answer

No removal of the tissue is necessary

Answer

Any of the above

Question 9

Which of the following is NOT a differential diagnosis for acute scrotum?

Accepted Answer

Testicular cancer

Answer

Epididymitis

Answer

Hydatid torsion

Answer

Testicular torsion

Question 10

Graft survival for the first 48 hours is primarily due to which of the following?

Accepted Answer

Absorption of nutrients into the graft

Answer

Alignment of donor and recipient capillaries

Answer

Vascularization of the graft

Answer

Growth of lymphatics into the graft

General Surgery Principles — MCQs

General Surgery Principles — MCQs

On this page

Practice by Chapter

Want unlimited practice?