Musculoskeletal Radiology Practice Questions

Q: Multiple lytic lesions of the skull with beveled edges are seen in:

Eosinophilic granuloma. ### Explanation **Correct Answer: A. Eosinophilic granuloma** **Why it is correct:** Eosinophilic granuloma (EG) is the most common and localized form of **Langerhans Cell Histiocytosis (LCH)**. The classic radiological hallmark in the skull is a "punched-out" lytic lesion. The characteristic **"beveled edge"** appearance occurs because the destruction of the inner table of the skull is more extensive than that of the outer table (or vice versa), creating slanted margins. When a central piece of bone remains within the lucency, it is termed a **"button sequestrum."** **Why the other options are incorrect:** * **B. Metastases:** While skull metastases (e.g., from breast or lung cancer) cause multiple lytic lesions, they typically have ill-defined, irregular margins and lack the specific beveled edge morphology. * **C. Multiple Myeloma:** This presents with multiple, uniform, "punched-out" lytic lesions that are typically small and sharply defined. However, they do not exhibit beveled edges or a button sequestrum. * **D. Neuroblastoma:** In children, metastatic neuroblastoma to the skull usually causes sutural widening (diastasis) and "hair-on-end" periosteal reaction rather than discrete beveled-edge lucencies. **High-Yield Clinical Pearls for NEET-PG:** * **LCH Triad (Hand-Schüller-Christian disease):** Exophthalmos, Diabetes Insipidus, and Bone lesions. * **Vertebra Plana:** EG is the most common cause of a single collapsed vertebral body (pancake vertebra) in children. * **Floating Teeth:** Mandibular involvement in LCH leads to loss of alveolar bone, making teeth appear as if they are floating. * **Birbeck Granules:** On electron microscopy, LCH cells show characteristic "tennis-racket" shaped granules.

Q: Wimberger ring sign is present in which condition?

Scurvy. **Explanation:** **Wimberger Ring Sign** is a classic radiographic feature of **Scurvy (Vitamin C deficiency)**. It refers to a thin, sclerotic (dense) rim of calcification surrounding a radiolucent (pale) epiphysis. This occurs because Vitamin C deficiency leads to defective osteoid formation; while the center of the epiphysis becomes osteoporotic and lucent, the zone of provisional calcification at the periphery remains dense, creating a "halo" or "ring" appearance. **Analysis of Options:** * **Scurvy (Correct):** In addition to Wimberger’s sign, other high-yield signs include **Frankel’s line** (dense zone of provisional calcification), **Trummerfeld zone** (lucent scorbutic zone), and **Pelkan spurs** (marginal osteophytes). * **Rickets:** Characterized by "Cupping, Fraying, and Splaying" of the metaphysis and an increased growth plate width. It does not feature the ring-like epiphyseal calcification seen in scurvy. * **Secondary Syphilis:** Typically presents with periostitis or "Wimberger’s **Sign**" (not Ring sign). *Note the distinction:* Wimberger’s sign in syphilis refers to localized bone destruction/erosion of the medial aspect of the proximal tibial metaphysis. * **Tuberculosis:** Usually presents with Phemister’s triad (juxta-articular osteopenia, peripheral joint erosions, and gradual joint space narrowing) or spinal involvement (Pott’s disease). **NEET-PG High-Yield Pearls:** * **Wimberger Ring Sign:** Scurvy (Epiphysis). * **Wimberger Sign:** Congenital Syphilis (Metaphysis). * **White line of Frankel:** Scurvy (dense metaphyseal line). * **Ground glass osteoporosis:** Common in Scurvy due to lack of collagen matrix.

Q: The Scottish terrier sign is typically observed in which radiographic view?

Oblique view. The **Scotty Dog (Scottish Terrier) sign** is a classic radiographic finding seen on **oblique views** of the lumbar spine. It is used to identify the integrity of the **pars interarticularis**. ### Why the Oblique View is Correct In a 45-degree oblique radiograph, the various components of the lumbar vertebrae align to resemble the silhouette of a Scottish Terrier dog: * **Eye:** Pedicle * **Nose:** Transverse process * **Ear:** Superior articular facet * **Foreleg:** Inferior articular facet * **Neck:** **Pars interarticularis** * **Body:** Lamina The clinical significance lies in the "neck" of the dog. A break or lucency in the neck indicates **spondylolysis** (a defect in the pars interarticularis). If the dog appears to be wearing a collar or is "decapitated," the diagnosis is confirmed. ### Why Other Options are Incorrect * **AP View:** Best for assessing vertebral body alignment, pedicle shadows ("winking owl sign"), and transverse processes, but it overlaps the posterior elements, making the pars difficult to visualize. * **PA View:** Similar to the AP view; it does not provide the necessary angular perspective to project the posterior elements in the "dog" configuration. * **Lateral View:** Best for assessing **spondylolisthesis** (forward slippage of vertebrae) and disc space height, but it does not clearly isolate the pars interarticularis from the surrounding bone as the oblique view does. ### NEET-PG High-Yield Pearls * **Spondylolysis:** A defect in the pars interarticularis (the "collar" on the dog). * **Spondylolisthesis:** Forward displacement of one vertebra over another; best graded using the **Meyerding Classification** on a **Lateral view**. * **Winking Owl Sign:** Seen on **AP view**; indicates destruction of a pedicle, often due to spinal metastasis. * **Bamboo Spine:** Classic for Ankylosing Spondylitis (seen on AP/Lateral views).

Q: 'Ring sign' is seen in:

Scurvy. The **'Ring sign'** (also known as **Wimberger’s sign**) is a classic radiological feature of **Scurvy** (Vitamin C deficiency). ### 1. Why Scurvy is Correct In Scurvy, there is a defect in osteoid formation due to impaired collagen synthesis. However, calcium deposition continues at the zone of provisional calcification. This results in a **dense, sclerotic rim** surrounding a radiolucent (osteoporotic) center of the epiphyseal ossification center. This appearance mimics a ring, hence the name 'Ring sign'. ### 2. Why Other Options are Incorrect * **Congenital Syphilis:** While it also features a "Wimberger’s sign," it is distinct. In syphilis, **Wimberger’s sign** refers to **destructive erosions of the medial aspect of the proximal tibial metaphysis**, not a ring-like epiphysis. * **Gaucher’s Disease:** The characteristic radiological finding here is the **'Erlenmeyer Flask deformity'** (flaring of the femoral metaphysis) and 'H-shaped' vertebrae due to bone marrow infiltration. ### 3. NEET-PG High-Yield Pearls for Scurvy Beyond the Ring sign, remember these high-yield radiological features of Scurvy: * **Frankel’s Line:** Dense white line at the metaphysis (zone of provisional calcification). * **Trummerfeld Zone:** A lucent "scurvy line" just proximal to Frankel’s line (representing a zone of debris/fracture). * **Pelkan Spur:** Marginal metaphyseal spurs caused by the healing of subperiosteal hemorrhages. * **Subperiosteal Hemorrhage:** Leads to significant periosteal elevation (visible during the healing phase).

Q: What is the abnormality shown in this shoulder radiograph?

Posterior dislocation of the shoulder. ***Posterior dislocation of the shoulder*** - Classic radiographic signs include the **"light bulb" sign** (fixed internal rotation of humeral head) and **trough line** (reverse Hill-Sachs lesion). - Shows **empty glenoid fossa** and **widened joint space** on AP view, distinguishing it from anterior dislocation. *Anterior dislocation of the shoulder* - Would show the humeral head positioned **inferior and medial** to the glenoid fossa on AP radiograph. - Associated with **Hill-Sachs lesion** (compression fracture of posterolateral humoral head), not the trough line seen in posterior dislocation. *Chondrosarcoma* - Appears as a **destructive bone lesion** with **chondroid matrix calcification** and soft tissue mass. - Shows **cortical destruction** and **aggressive bone changes**, not joint displacement or dislocation. *Simple bone cyst* - Presents as a **well-defined, lytic lesion** in the metaphysis with **thin cortical margins**. - Typically occurs in **proximal humerus** of children/adolescents, appearing as a fluid-filled cavity without joint involvement.

Q: In a patient presenting with shoulder pain and no clear history of trauma, what does this radiograph most likely suggest?

Calcific tendinitis. ***Calcific tendinitis*** - Radiograph shows **calcium deposits** within the **supraspinatus tendon** or other rotator cuff tendons, appearing as dense white opacities near the greater tuberosity. - Clinical presentation of **shoulder pain without trauma** is characteristic, often with **night pain** and restricted range of motion. *Shoulder dislocation* - Would show **loss of normal humeral head-glenoid relationship** with the humeral head positioned anteriorly, posteriorly, or inferiorly relative to the glenoid fossa. - Typically presents with **severe pain**, **inability to move the arm**, and obvious deformity following trauma. *Acromioclavicular dislocation* - Radiograph would demonstrate **separation** or **step-off** between the **acromion** and **distal clavicle** at the AC joint. - Usually results from **direct trauma** to the shoulder, such as a fall onto the lateral aspect of the shoulder. *Hill-Sachs lesion* - Appears as a **compression fracture** of the **posterolateral humeral head**, creating an indentation or flattening on the bone surface. - Associated with **anterior shoulder dislocation** and would require a history of significant trauma or recurrent dislocations.

Q: What is the possible diagnosis based on the provided X-ray image?

Osgood-Schlatter disease. ***Osgood-Schlatter disease*** - X-ray shows **tibial tuberosity fragmentation** and **irregularity** on lateral knee view, characteristic of this condition in adolescents - Presents as **anterior knee pain** below the patella with **tibial tubercle prominence** in active adolescents during growth spurts *Pellegrini-Stieda lesion* - Appears as **calcification** along the **medial collateral ligament** attachment at the medial femoral condyle on AP knee X-ray - Results from **chronic MCL injury** and shows **linear calcification** rather than tibial tuberosity changes *SLAP tear* - **Superior labrum anterior-posterior tear** of the shoulder **glenoid labrum** cannot be diagnosed on plain X-rays - Requires **MRI** or **MR arthrography** for visualization as it involves **soft tissue structures** not visible on X-ray *Segond fracture* - Shows as a **small avulsion fracture** of the **lateral tibial plateau** on AP knee X-ray - Associated with **ACL injury** and appears as a **small bony fragment** at the lateral joint line, not tibial tuberosity

Q: Which of the following lesions has a radiographic soap bubble appearance, with a characteristic feature of 'pumping action'?

Central hemangioma. **Explanation:** The correct answer is **Central Hemangioma**. This is a rare intraosseous vascular malformation, most commonly involving the mandible. **1. Why Central Hemangioma is correct:** Radiographically, central hemangiomas often present as a multilocular radiolucency with a **"soap bubble," "honeycomb," or "sunburst" appearance**. The pathognomonic clinical feature mentioned is the **"pumping action" or "pumping phenomenon."** This occurs because the lesion is highly vascular and under arterial pressure; if a needle is inserted or pressure is applied, the plunger of the syringe may be pushed back spontaneously, or the tooth within the lesion may exhibit a rhythmic pulsation. **2. Why other options are incorrect:** * **Ameloblastoma:** While it classically presents with a "soap bubble" or "honeycomb" appearance, it is a benign epithelial tumor, not a vascular one. It lacks the pulsatile "pumping action." * **Central Giant Cell Granuloma (CGCG):** This typically shows a multilocular radiolucency with wispy, ill-defined septations. It does not exhibit vascular pulsations. * **Odontogenic Keratocyst (OKC):** Known for its characteristic growth along the internal aspect of the jaw (anteroposterior expansion) with minimal cortical expansion, it does not show the pumping phenomenon. **High-Yield Pearls for NEET-PG:** * **Aspiration is mandatory:** Always aspirate any suspected multilocular radiolucency before biopsy to rule out central hemangioma, as surgical intervention can lead to life-threatening hemorrhage. * **Radiographic variants:** Central hemangiomas can also show a **"Spoke-wheel"** appearance or **"Sunray"** appearance (radiating striae from a central point). * **Phleboliths:** The presence of small, rounded calcifications (phleboliths) within soft tissues is a diagnostic clue for vascular lesions.

Question 1

Vertebra plana is seen in which of the following conditions?

Accepted Answer

Paget's disease

Answer

Eosinophilic granuloma

Answer

Trauma

Answer

Malignancy

Question 2

Multiple lytic lesions of the skull with beveled edges are seen in:

Accepted Answer

Eosinophilic granuloma

Answer

Metastases

Answer

Multiple myeloma

Answer

Neuroblastoma

Question 3

Which one of the following conditions is not associated with cupping and fraying of metaphyses of long bones in children?

Accepted Answer

Lead poisoning

Answer

Rickets

Answer

Metaphyseal dysplasia

Answer

Hypophosphatasia

Question 4

Wimberger ring sign is present in which condition?

Accepted Answer

Scurvy

Answer

Rickets

Answer

Secondary syphilis

Answer

Tuberculosis

Question 5

The Scottish terrier sign is typically observed in which radiographic view?

Accepted Answer

Oblique view

Answer

Anteroposterior (AP) view

Answer

Posteroanterior (PA) view

Answer

Lateral view

Question 6

'Ring sign' is seen in:

Accepted Answer

Scurvy

Answer

Congenital syphilis

Answer

Gaucher's disease

Answer

All of the above

Question 7

What is the abnormality shown in this shoulder radiograph?

Accepted Answer

Posterior dislocation of the shoulder

Answer

Anterior dislocation of the shoulder

Answer

Chondrosarcoma

Answer

Simple bone cyst

Question 8

In a patient presenting with shoulder pain and no clear history of trauma, what does this radiograph most likely suggest?

Accepted Answer

Calcific tendinitis

Answer

Shoulder dislocation

Answer

Acromioclavicular dislocation

Answer

Hill-Sachs lesion

Question 9

What is the possible diagnosis based on the provided X-ray image?

Accepted Answer

Osgood-Schlatter disease

Answer

Pellegrini-Stieda lesion

Answer

SLAP tear

Answer

Segond fracture

Question 10

Which of the following lesions has a radiographic soap bubble appearance, with a characteristic feature of 'pumping action'?

Accepted Answer

Central hemangioma

Answer

Central Giant Cell Granuloma (CGCG)

Answer

Ameloblastoma

Answer

Odontogenic keratocyst (OKC)

Musculoskeletal Radiology — MCQs

Musculoskeletal Radiology — MCQs

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