PET Radiochemistry — MCQs

A pregnant woman with head trauma requires a CT scan of the head. What is the most effective radiation protection measure for the fetus?

Which of the following is the platinum-based chemotherapeutic agent used as first-line treatment for ovarian carcinoma?

A lady presented with a 4 cm tumor in the left parietal lobe for which she underwent surgery and radiotherapy. After 3 months she presented with headache and vomiting. Which of the following would characterize the lesion in the patient?

The substance most commonly used for protection against X-ray radiation is?

The most appropriate first-line imaging modality to detect adrenal metastasis due to bronchogenic carcinoma is:

A research team is developing a new radiotracer for imaging hypoxia in tumors. They need to select between 18F-labeled and 64Cu-labeled versions of the same molecule. Considering half-lives (18F: 110 min, 64Cu: 12.7 hours), positron ranges, and clinical applicability, which choice and rationale is most appropriate?

A 58-year-old woman with gastrinoma undergoes both FDG-PET and 68Ga-DOTATATE PET scans. FDG-PET shows minimal uptake (SUVmax 2.1) while DOTATATE scan shows intense uptake (SUVmax 45). What does this pattern indicate about tumor biology?

A 65-year-old man with known lung cancer undergoes FDG-PET scan. The scan shows intense FDG uptake (SUVmax 8.5) in the primary lung mass and a 1.2 cm mediastinal lymph node with SUVmax 4.2. What is the most appropriate interpretation?

How does 68Ga-DOTATATE molecular imaging differ from FDG-PET in mechanism of tumor detection?