Molecular Basis of Enzyme Function — MCQs

Assertion: RMP depends on proteins and phosphate ions. Reason: Diffusion potential can be calculated using nernst equation. Choose the best statement regarding the assertion and reason.

Which of the following is true about non-competitive inhibition?

Which of the following is an example of allosteric inhibition?

Which of the following statements about isozymes is true?

Identify the false statement regarding suicide inhibition

What is the specific activity of an enzyme?

Enzymes that move a molecular group from one molecule to another are known as -

The primary hormone secreted by duodenal cells in response to dietary fats and proteins is:

A novel drug is designed to treat a genetic disorder caused by a nonsense mutation in the dystrophin gene. The drug works by allowing the ribosome to skip over the premature stop codon and continue translation. Evaluation of this therapeutic strategy reveals partial restoration of dystrophin protein with 60% of normal length but sufficient function. What is the most critical molecular consideration in determining if this approach will be clinically beneficial?

A 45-year-old woman with breast cancer is being treated with trastuzumab (Herceptin). Laboratory analysis of her tumor cells shows 100-fold amplification of a specific gene. Analysis of the signal transduction pathway reveals constitutive activation of PI3K/AKT pathway. Which receptor is most likely overexpressed?