Antimicrobial Agents — MCQs

A 6-year-old girl is diagnosed with meningitis. A lumbar puncture reveals numerous neutrophils and gram-negative diplococci. She is admitted to the hospital for antibiotic treatment, which is complicated by the fact that she is known to be allergic to beta-lactams. What is the mechanism of action of the alternative drug of choice to treat this child's meningitis?

A 5-year-old female presented to the emergency department with fever, headache, and confusion. A provisional diagnosis of bacterial meningitis was made. The patient had a severe allergic reaction to penicillin approximately six months prior. She was admitted and intravenous antibiotics were started. A few days later, her investigations revealed: Hemoglobin 6.0 g/L, Erythrocyte count 1.2 x 10^6/mm^3, Platelets 60,000/mm^3, Leukocyte count 1500/mm^3. Which of the following is the most likely drug responsible for the above findings?

A contraindication to the use of ciprofloxacin is a history of:

Ciprofloxacin acts on which of the following targets?

What is the drug of choice for CMV retinitis in patients with AIDS?

Which of the following cephalosporins is not active against anaerobes?

Which ototoxic drug primarily affects the vestibular component?

Which is the drug of choice for the following condition?

Which antitubercular drug combination is safer in a patient who develops hepatitis while on ATT?

A 36-year-old woman, recently treated for leukemia, is admitted with malaise, chills, and high fever. Gram stain of blood reveals gram-negative bacilli. The initial diagnosis is bacteremia, and parenteral antibiotics are indicated. The patient's record shows a severe urticarial rash, hypotension, and respiratory difficulty after oral penicillin V 6 months ago. What is the most appropriate drug to administer?