Question 1

Q: A patient develops pulmonary thromboembolism most commonly due to what?

Deep Vein Thrombosis (DVT). ***Deep Vein Thrombosis (DVT)*** - **Deep vein thrombosis (DVT)** is the most common cause of pulmonary thromboembolism, as clots from deep veins, typically in the legs, travel to the lungs [1]. - The initial clot formation in DVT is often multifactorial, involving elements of **Virchow's triad** (venous stasis, endothelial injury, and hypercoagulability) [1]. *Chronic Venous Hypertension* - **Chronic venous hypertension** results from sustained high pressure in leg veins, leading to symptoms like edema, skin changes, and ulcers, but does not directly cause emboli. - It's a consequence of venous insufficiency and doesn't involve the formation of typical occlusive thrombi that can embolize to the pulmonary arteries. *Disseminated intravascular coagulation (DIC)* - **Disseminated intravascular coagulation (DIC)** is a severe, systemic condition characterized by widespread activation of coagulation, leading to microthrombi formation and consumption of clotting factors, often resulting in bleeding. - While small thrombi can form, the primary manifestation is diffuse bleeding, and the thrombi are usually diffuse microvascular clots rather than large, embolizing thrombi to the pulmonary arteries. *Inherited Thrombophilia* - **Inherited thrombophilias** are genetic predispositions to excessive clotting and are risk factors for DVT, but they are not the direct cause of pulmonary embolism. - They increase the likelihood of developing DVT, which then *in turn* can lead to pulmonary embolism [1].

Question

A patient develops pulmonary thromboembolism most commonly due to what?

Accepted Answer

Deep Vein Thrombosis (DVT)

Answer

Chronic Venous Hypertension

Answer

Disseminated intravascular coagulation (DIC)

Answer

Inherited Thrombophilia

Respiratory Pathology — MCQs

Respiratory Pathology — MCQs

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