Reproductive Pathology — MCQs

What is a blighted ovum?

What is true about endodermal sinus tumors?

Biopsy of a persistent exophytic area on the vulva of a 60-year-old woman demonstrates a squamous epithelial lesion. No koilocytes are seen. The lesions show papillary projections composed of disordered squamous epithelium with well-differentiated cells. The basement membrane at the dermal-epidermal junction is focally disrupted by squamous cell groups extending deep into the dermis. Which of the following diagnoses is most accurate?

Which of the following is usually bilateral carcinoma of the breast?

E-cadherin mutation is seen in the metastasis of which type of breast carcinoma?

Testicular teratoma in adults is generally considered?

Which testicular tumor has the best prognosis?

Extramammary Paget's disease is typically seen in which of the following locations?

A 45-year-old woman develops abdominal and pelvic discomfort. Physical examination reveals a large mass in the right lower quadrant, which is surgically resected. The mass consists of a large (25 cm) cystic sac containing thick mucinous fluid within a thin wall. On careful inspection, the pathologist finds an area of increased thickness in the cyst wall, which is sampled for histology. Microscopically, the tumor appears to be composed mostly of a single layer of nonciliated columnar cells arranged in papillary projections. The thickened area, however, displays stratification of epithelial cells, increased cytologic atypia, and high mitotic activity. Nevertheless, no stromal invasion is found. Which of the following is the most likely diagnosis?

Intrauterine exposure of diethylstilbestrol is associated with which of the following conditions?