Molecular Pathology — MCQs

An 11-year-old girl becomes infected with hepatitis A and experiences mild nausea for 1 week. On physical examination, she has minimal right upper quadrant tenderness and scleral icterus. Laboratory findings include a serum AST of 68 U/L, ALT of 75 U/L, and total bilirubin of 5.1 mg/dL. Her laboratory findings most likely result from which of the following changes in her hepatocytes?

Which of the following produces irreversible cell injury faster?

A 60-year-old farmer presents with multiple patches of discoloration on his face. Biopsy of lesional skin reveals actinic keratosis. Which of the following terms best describes this response of the skin to chronic sunlight exposure?

Which of the following is not a sign of reversible cell injury?

Cell swelling is seen in all conditions except?

In an experiment, metabolically active cells are subjected to radiant energy in the form of x-rays. This results in cell injury caused by hydrolysis of water. Which of the following intracellular enzymes helps to protect the cells from this type of injury?

Which method is used to detect the BCR-ABL fusion gene?

Which of the following is NOT an advantage of nanotechnology in cancer diagnosis?

A 38-year-old woman shows evidence of early cataracts, hair loss, atrophy of skin, osteoporosis, and accelerated atherosclerosis. This patient has most likely inherited mutations in both alleles of a gene that encodes which of the following types of intracellular proteins?

The difference between an active cell and a resting cell depends on which phase of the cell cycle?