Molecular Pathology — MCQs

Lipofuscin-containing macrophages are a characteristic feature of which process?

ALK translocation is a characteristic pathogenic mechanism in which of the following conditions?

What is the term for the well-organized and internally programmed death of a cell?

Alpha-1-antitrypsin deficiency is associated with which chromosome?

What is the primary cause of reperfusion injury?

Which of the following is an immunohistochemical marker for neuroendocrine tumors?

Submicroscopic deletions of any size can be detected by which of the following methods?

Which of the following is NOT a pathologic effect of free radicals?

A 16-year-old boy sustained blunt trauma to his abdomen. Peritoneal lavage shows a hemoperitoneum, and at laparotomy, a portion of the injured liver is removed. Two months later, a CT scan of the abdomen shows that the liver has nearly regained its size before the injury. Which of the following processes best explains this finding?

A 33-year-old woman presents with a one-week history of increasing lethargy and decreased urine output. Laboratory studies reveal a serum creatinine of 4.3 mg/dL and blood urea nitrogen of 40 mg/dL. A renal biopsy is performed and examined using electron microscopy. Which of the following morphologic cellular changes most likely suggests a diagnosis of acute tubular necrosis?