Infectious Diseases Practice Questions

Q: Torres bodies are seen in which of the following conditions?

Yellow fever. **Explanation:** **Yellow Fever (Correct Answer):** Torres bodies are characteristic **intranuclear eosinophilic inclusion bodies** found in the hepatocytes of patients with Yellow Fever. They represent viral nucleocapsids and are often seen alongside **Councilman bodies**, which are eosinophilic globules representing apoptotic hepatocytes (acidophilic degeneration). These findings are hallmark pathological features of the mid-zonal necrosis typically seen in the liver during Yellow Fever infection. **Analysis of Incorrect Options:** * **Kala-azar (Visceral Leishmaniasis):** Characterized by **LD bodies** (Leishman-Donovan bodies), which are amastigote forms of the parasite found within the macrophages of the reticuloendothelial system (spleen, liver, bone marrow). * **HSV (Herpes Simplex Virus):** Characterized by **Cowdry Type A** inclusions (intranuclear eosinophilic bodies surrounded by a clear halo) and "ground-glass" nuclei. * **EBV (Epstein-Barr Virus):** Associated with **atypical lymphocytes** [2] (Downey cells) in the peripheral blood smear. It does not produce Torres bodies. **High-Yield Clinical Pearls for NEET-PG:** * **Yellow Fever Triad:** Mid-zonal necrosis, Councilman bodies, and Torres bodies. * **Councilman bodies** are not pathognomonic for Yellow Fever; they can be seen in other forms of viral hepatitis [1], but **Torres bodies** are more specific. * **Negri bodies:** Seen in Rabies (intracytoplasmic, Hippocampus/Purkinje cells). * **Guarnieri bodies:** Seen in Smallpox (intracytoplasmic). * **Henderson-Paterson bodies:** Seen in Molluscum Contagiosum. **References:** [1] Cross SS. Underwood's Pathology: A Clinical Approach. 6th ed. Common Clinical Problems From Liver And Biliary System Disease, pp. 390-391. [2] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Infectious Diseases, pp. 369-370.

Question 1

Torres bodies are seen in which of the following conditions?

Accepted Answer

Yellow fever

Answer

Kala azar

Answer

HSV

Answer

EBV

Question 2

Which of the following conditions is characterized by caseating necrosis?

Accepted Answer

Tuberculosis

Answer

Leprosy

Answer

Sarcoidosis

Answer

Infarct

Question 3

Which virus is implicated in Burkitt's lymphoma?

Accepted Answer

EBV

Answer

HTLV

Answer

HPV

Answer

HHV8

Question 4

What is septicemia?

Accepted Answer

Multiplication of bacteria and toxins in the blood

Answer

Bacteria in the blood

Answer

Toxins in the blood

Answer

Pus in the blood

Question 5

Reactivation of TB is most commonly located near which anatomical area?

Accepted Answer

Apex

Answer

Bronchus

Answer

Subpleural space

Answer

Base

Question 6

Which of the following conditions is characterized by granulomas with stellate abscesses?

Accepted Answer

All of the above

Answer

Tuberculosis

Answer

Tularemia

Answer

Sarcoidosis

Question 7

Cachectin is produced by which of the following cells?

Accepted Answer

Macrophages

Answer

Neutrophils

Answer

Eosinophils

Answer

Basophils

Question 8

Intranuclear viral inclusions are seen in tissue specimens of which of the following conditions?

Accepted Answer

Hairy leukoplakia

Answer

Solar cheilitis

Answer

Minor aphthous ulcers

Answer

Geographic tongue

Question 9

Which of the following is NOT an example of a granulomatous disease?

Accepted Answer

Mycoplasma infection

Answer

Tuberculosis

Answer

Leprosy

Answer

Sarcoidosis

Question 10

HIV infection is known to cause which of the following renal pathologies?

Accepted Answer

Collapsing glomerulonephritis

Answer

Membranous glomerulonephritis

Answer

Fibrillary glomerulopathy

Answer

Rapidly progressive glomerulonephritis (RPGN)

Infectious Diseases — MCQs

Infectious Diseases — MCQs

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