Immunopathology — MCQs

Which of the following is true about Graft-versus-Host Disease (GVHD)?

Which of the following statements is not true regarding Ataxia telangiectasia?

A patient with sarcoidosis has non-caseating granulomas. Which type of hypersensitivity reaction is responsible for developing granulomatous inflammation in this patient?

Which cells are responsible for forming circulating antibodies?

A 39-year-old woman presents with acute onset of severe dyspnea. Physical examination reveals she is afebrile with marked laryngeal stridor and severe airway obstruction. Her medical history indicates similar episodes since childhood and episodes of colicky gastrointestinal pain. Her mother and brother are similarly affected. There is no history of severe or recurrent infections, and she does not have urticaria. Laboratory studies show a normal WBC count, hematocrit, and platelet count. A deficiency in which of the following plasma components is most likely to produce these findings?

A 2-year-old boy has had almost continuous infections since he was 6 months old. These infections have included otitis media, pneumonia, and impetigo. Organisms cultured include Haemophilus influenzae, Streptococcus pneumoniae, and Staphylococcus aureus. He also has had diarrhea, with Giardia lamblia cysts identified in stool specimens. The family history indicates that an older brother with a similar condition died because of overwhelming infections. The boy's two sisters and both parents are not affected. Which of the following laboratory findings would most likely be seen in this boy?

A 35-year-old man presents with complaints of seasonal eye itching and a runny nose. Recurrent conjunctivitis in this patient is most likely caused by which of the following mechanisms?

Which interleukin functions as a T-cell growth factor?

Which of the following is false regarding hereditary angioneurotic edema?

Which marker indicates Natural Killer (NK) cell activity?