Adaptive Immunity Practice Questions

Question 1

Which of the following is not considered an antigen-presenting cell?

Accepted Answer

Thymocytes

Answer

Macrophages

Answer

Langerhans cells

Answer

B lymphocytes

Question 2

Which of the following statements about the secondary immune response is false?

Accepted Answer

Immune response against a subsequent antigenic challenge is absent.

Answer

The lag period is absent or significantly shorter.

Answer

There is a negative phase in the response.

Answer

Only T-dependent antigens are recognized.

Question 3

What is the primary mechanism by which cytotoxic T lymphocytes (CTLs) recognize target cells in the immune response?

Accepted Answer

Recognize antigens presented by MHC class I molecules

Answer

Are important in the control of viral infections

Answer

Secrete cytokines that stimulate the differentiation and proliferation of T cells

Answer

Most often recognize antigens presented by MHC class II molecules

Question 4

Which of the following is not a component of innate immunity?

Accepted Answer

Helper T lymphocytes

Answer

Epithelial barriers

Answer

NK cells

Answer

Dendritic cells

Question 5

MHC II is associated with:-

Accepted Answer

Antigen presenting cells

Answer

Red blood cells

Answer

Platelets

Answer

Epithelial cells

Question 6

Which is the cell of origin of Chronic Lymphocytic Leukaemia / Small Lymphocytic Lymphoma?

Accepted Answer

Naïve B cells

Answer

Mature B cells

Answer

Progenitor T cells

Answer

Mature T cells

Question 7

t(2,8) is associated with:

Accepted Answer

B cell ALL

Answer

T cell ALL

Answer

CML

Answer

CLL

Question 8

Adoptive immunity is by what mechanism?

Accepted Answer

Injection of lymphocytes

Answer

Vaccination with killed pathogens

Answer

Natural infection

Answer

Passive transfer of antibodies

Question 9

What are the changes in the variable region of immunoglobulins?

Accepted Answer

Idiotype

Answer

Isotype

Answer

Epitope

Answer

Allotype

Question 10

Histamine in anaphylaxis is secreted by which of the following cells?

Accepted Answer

Mast cells

Answer

B-cells

Answer

Basophils

Answer

Macrophages

Adaptive Immunity — MCQs

Adaptive Immunity — MCQs

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