Hematopathology — MCQs

Leukoreduced blood products have lower WBCs than normal by what fold?

Which of the following conditions is not typically associated with leucocytosis?

Which of the following is NOT an immunohistochemical marker of Langerhans cell histiocytosis?

At autopsy, the spleen of a patient is noted to have a thickened capsule and many small, scarred areas. Microscopic examination of the scarred areas reveals fibrosis with hemosiderin and calcium deposition. This type of spleen is usually seen in conjunction with which of the following disorders?

A child with prolonged aPTT, who underwent laparotomy without bleeding complications, is most likely to have a deficiency in which clotting factor?

A 62-year-old man reports early satiety, fatigue, and generally feeling unwell. The symptoms started gradually and are getting worse. He notes no chest discomfort, respiratory symptoms, or abdominal pain. On physical examination, he appears pale, the vital signs are normal, and the pertinent findings are a large spleen, absence of lymph nodes, and normal heart and lungs. His blood count is abnormal; the WBC is 50,000/mL with increased mature granulocytes, hemoglobin is 9.5 g/dL, and platelets are 450,000/mL. Which of the following cytogenetic changes is most characteristic of his condition?

A child is diagnosed with Burkitt's Lymphoma. The presence of which of the following translocations confirms the diagnosis?

Platelet dense granules contain all except?

A patient presents with bone pain. X-ray reveals destructive lesions. Laboratory investigations show hypercalcemia. Serum electrophoresis shows M spike, while bone marrow shows 35% plasma cells. What is your diagnosis?

Oxidative injury of the red blood cells leading to hemolysis is associated with which of the following clinical conditions?