Hematopathology — MCQs

All of the following NHL involve the white pulp of the spleen EXCEPT?

Which of the following conditions features an intrinsic cell wall defect of red blood cells?

What is the primary treatment for Kostmann's syndrome?

Patients with Immune Thrombocytopenic Purpura (ITP) have antibodies to which of the following?

A 70-year-old male presented with a 3-month history of generalized weakness. On examination, bilateral axillary lymphadenopathy was noted. Histopathological examination of the enlarged lymph node showed effacement of the lymph node architecture by a diffuse proliferation of small-sized, mature-appearing lymphoid cells. Peripheral blood showed lymphocytosis with the presence of CD5-positive and CD23-positive B-cells. Which of the following is the most likely diagnosis in this patient?

Burkitt's lymphoma arises from which cell type?

CD59 deficiency leads to which condition?

A 55-year-old man presents with a 1-week history of a lump near his shoulder. Physical examination reveals an enlarged, nontender, supraclavicular lymph node and enlargement of the Waldeyer ring of oropharyngeal lymphoid tissue. There is no hepato-splenomegaly. A complete blood count is normal except for findings of mild anemia. A lymph node biopsy specimen shows replacement by a monomorphous population of lymphoid cells that are twice the size of normal lymphocytes, with enlarged nuclei and prominent nucleoli. Immunohistochemical staining and flow cytometry of the node indicate that most lymphoid cells are CD19+, CD10+, CD3-, CD15-, and terminal deoxynucleotidyl transferase negative (TdT-). A BCL6 gene mutation is present. Which of the following is the most likely diagnosis?

Pure red cell aplasia is associated with which of the following conditions?

Sickle cell anemia is due to: