Hematopathology — MCQs

What condition is characterized by an M spike on serum electrophoresis?

Which of the following statements is true regarding Chronic Myeloid Leukemia (CML)?

What are the typical Antithrombin III levels in disseminated intravascular coagulation?

During blood transfusion, clotting of transfused blood is associated with which of the following?

Chediak Higashi syndrome is characterized by which of the following defect of platelets?

A 54-year-old male presents with massive splenomegaly, early fatigue, malaise, low-grade fever, gout, increased susceptibility to infections, anemia, a total leukocyte count of 125,000/mm³, and thrombocytopenia with easy bruising. Which chromosomal translocation is most commonly associated with this diagnosis?

A 48-year-old woman presented with a two-month history of weakness. On examination, cervical lymph nodes were enlarged, and the spleen was palpable 2 cm below the costal margin. Her hemoglobin was 10.5 g/dL, platelet count was 237 x 10^9/L, and total leukocyte count was 40 x 10^9/L, which included 80% mature lymphoid cells with coarse clumped chromatin. Bone marrow revealed a nodular lymphoid infiltrate. The peripheral blood lymphoid cells were positive for CD19, CD5, CD20, and CD23 and were negative for CD79b and FMC-7. What is the most likely diagnosis?

Which of the following is NOT typically seen in hemolytic anemia?

Destruction of Heinz bodies in the spleen is performed by which cells?

A 40-year-old male who underwent splenectomy 20 years ago presents for a peripheral blood smear examination. What would be observed?