Hematopathology — MCQs

Which tumor is most rapidly metastatic?

A single nucleotide change in a codon on chromosome 11 causes valine to replace glutamic acid at the sixth position of the beta chain of hemoglobin. What is the resulting condition?

Leukoreduced blood products have lower WBCs than normal by what fold?

Which of the following conditions is not typically associated with leucocytosis?

Which of the following is NOT an immunohistochemical marker of Langerhans cell histiocytosis?

At autopsy, the spleen of a patient is noted to have a thickened capsule and many small, scarred areas. Microscopic examination of the scarred areas reveals fibrosis with hemosiderin and calcium deposition. This type of spleen is usually seen in conjunction with which of the following disorders?

A child with prolonged aPTT, who underwent laparotomy without bleeding complications, is most likely to have a deficiency in which clotting factor?

A child is diagnosed with Burkitt's Lymphoma. The presence of which of the following translocations confirms the diagnosis?

Which one of the following statements about thalassemia is not true?

A patient presents with bone pain. X-ray reveals destructive lesions. Laboratory investigations show hypercalcemia. Serum electrophoresis shows M spike, while bone marrow shows 35% plasma cells. What is your diagnosis?